Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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Patent•
09 Nov 1992
TL;DR: In this article, the authors proposed a solution for the treatment and prophylaxis of cardiovascular diseases using trifluoromethyl or pentafluoroethyl compounds.
Abstract: Compounds of the formula: ##STR1## in which: R 1 is a trifluoromethyl or a pentafluoroethyl; R 2 is ##STR2## in which R 4 is hydrogen; α-β is a carbon-carbon single bond; and pharmaceutically acceptable salts thereof, have antihypertensive activity and can thus be used for the treatment and prophylaxis of cardiovascular diseases.
3 citations
3 citations
01 Jan 2000
3 citations
Journal Article•
TL;DR: In this paper, the synthesis of hitherto unreported bischromone 6 has been accomplished and their reactions with methanol under neutral, acidic and basic condition are reported, but their results are limited.
3 citations
TL;DR: In this paper, 4-heterocyclic substituted coumarin derivatives are screened for antiinflammatory activity in vitro through their antiproteolytic activity, the interaction with 1,1-diphenyl-2-picrylhydrazyl and the ability to affect superoxide anion and to inhibit β-glucuronidase and soybean lipoxygenase.
Abstract: 1,3-Cycloaddition reactions of new 2-oxo-2H-[1]benzopyran-4-carbonitrile N-oxide 2 with dipolarophiles, o-aminophenols and o-phenylenediamine resulted in 4-heterocyclic substituted coumarin derivatives. These derivatives are screened for antiinflammatory activity in vitro through their antiproteolytic activity, the interaction with 1,1-diphenyl-2-picrylhydrazyl and the ability to affect superoxide anion and to inhibit β-glucuronidase and soybean lipoxygenase.
3 citations