Benzopyran

About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.

Method for synthesizing chiral spirocyclo-oxindole-benzopyran-ketone-3,4-dihydro-pyran compound

Abstract: The invention discloses a method for synthesizing a chiral spirocyclo-oxindole-benzopyran-ketone-3,4-dihydro-pyran compound. The method comprises the following steps: using an isatin derivative beta, gama-unsaturated alpha-keto ester and 3-hydroxy-4-hydrogen-chromene-4-ketone as reactants, and synthesizing in a solvent under the catalysis of chiral multifunctional chiral quinine thiourea to obtain a product. The method provided by the invention has the advantages of simple and easy obtaining of raw materials, mild reaction conditions, simple and convenient post-treatment, wide range of suitable substrates, high yield and high enantioselectivity, and the synthesized product can be used for synthesizing intermediates of drugs, insecticides and photoelectric materials.

Benzopyran peptide derivative assuming antioxidizing action, and method for producing the same

Abstract: PROBLEM TO BE SOLVED: To provide a benzopyran peptide derivative assuming excellent antioxidizing actions with weak adverse effects, and to provide a method for producing the benzopyran peptide derivative thereof. SOLUTION: The benzopyran peptide derivative assuming excellent antioxidizing actions with the weak adverse effects binds to a peptide composed of benzopyran, L-type threonine and L-type cysteine. In the derivative, a hydroxy group of threonine binds to p-coumaric acid, and caprylic acid further binds through an ester bond. Thereby, the derivative has excellent lipophilicity and antioxidizing properties. When excessively ingested, the safety is high because the derivative is degraded with an esterase. The method for production thereof is characterized by steps of adding a Beni-koji mold to Hippophae rhamnoides and soybean powder, fermenting the resultant material, and reducing the obtained fermentation liquor with an alkali. The fermentation step and the reducing step are main steps. COPYRIGHT: (C)2009,JPO&INPIT

Structure and absolute configuration of nebivolol: (±)‐(R*{S*[S*‐(S*)]})‐α,α'‐[iminobis(methylene)]bis(6‐fluoro‐3,4‐dihydro‐2H‐1‐benzopyran‐2‐methanol) (nebivolol) hydrochloride (I) and (+)‐(S{R[R‐(R)]})‐nebivolol hydrobromide dihydrate (II)

Abstract: Both structures, C 22 H 26 F 2 NO 4 + .Cl - (1) and C 22 H 26 F 2 -NO 4 + .Br - .2H 2 O (II), have essentially the same conformation. The bridging chain between the two benzopyran moieties is nearly fully extended. In each molecule one O-C-C-O dihedral angle is synclinal and the other is antiperiplanar. One hydropyran ring has a halfchair conformation while the other is halfway between half-chair and envelope. The structures are stabilized by hydrogen-bonding networks. The absolute configuration of the molecule was determined from the structure of (II)

Benzopyran-based compound and its production

Abstract: PROBLEM TO BE SOLVED: To obtain a new compound useful for a red-based fluorescent coloring matter having high excellent characteristics such as emission brightness, fastness and excellent luminous efficiency suitable in the field of an organic electric field light emission element. SOLUTION: This compound is shown by formula [R1 to R4 are each H or a 1-4C alkyl; ring Z is a (substitute) aromatic ring] such as a compound of formula II. The compound of formula I is obtained by reacting a compound of formula III (e.g. 1,1,7,7-tetramethyl-8-hydroxy-9-formyljulolidine, etc.), with a compound of formula IV (e.g. 2-benzimidazolylacetonitrile, etc.), generally in an inert solvent such as N,N-dimethylformamide, etc., in the presence of an inorganic or an organic basic condensation agent preferably at 0-50 deg.C for about 0.5-48 hours to synthesize a compound of formula V, then reacting the compound with malononitrile preferably at 50-200 deg.C for 0.5-48 hours and hydrolyzing the formed compound.