Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: In this article, isorotenone (Ib) was used to obtain 4-hydroxycoumarin (Vb) for use in metabolic and other studies, which was transformed into the 14C-labeled benzofurano [2,3-b]furo[2, 3]benzopyran-6-one compound (IVb) by the subsequent oxidative cyclization with selenium dioxide.
Abstract: 2-Isopropyl-8,9-dimethoxy-benzofurano [2,3-b]furo[2,3-h] [1] [11-14C]benzopyran-6-one (IVb) and 3-(2-hydroxy-4,5-dimethoxyphenyl)-4-hydroxy-5′-isopropylfurano[2′,3′:7,8] [2-14C]coumarin(Vb) were prepared from isorotenone (Ib) for use in metabolic and other studies. Deoxybenzoin derivative (IIb), obtained from isorotenone, was reacted with ethyl [14C] formate in the presence of sodium to give the corresponding [2-14C]-2′-hydroxyisoflavone (IIIb), which was transformed into the 14C-labeled benzofurano [2,3-b]furo[2,3-h]benzopyran-6-one compound (IVb) by the subsequent oxidative cyclization with selenium dioxide. Hydrolysis of compound IVb in alkaline media gave 14C-labeled 4-hydroxycoumarin (Vb).
2 citations
Journal Article•
2 citations
TL;DR: The title compound, C(16)H(19)BrO(4), is a derivative of osthol, isolated from the seeds of Imperatoria Osthruthium, and was refined to a final R factor of 0.064.
Abstract: The title compound, C(16)H(19)BrO(4), is a derivative of osthol, isolated from the seeds of Imperatoria Osthruthium. The structure was solved in space group P-1, with two molecules in the asymmetric unit, and was refined to a final R factor of 0.064. The two molecules in the asymmetric unit differ in the orientation of their brominated substituent group. The benzopyran ring displays aromatic character. The packing of the molecules in the lattice is mainly due to C-H...O hydrogen bonds.
2 citations
Patent•
05 Jul 1995
2 citations
Patent•
25 Jun 2002
TL;DR: A benzopyran derivative represented by the general formula (I): wherein R 1 is an alkyl group having 1-10 carbon atoms or an alkenyl group having 2-10 atoms, and one of R 2, R 3, R 4, and R 5 is an alkoxy group substituted with a hydroxygroup or an alkoxyl group substituting with a carboxy group, and the others are hydrogen atoms or physiologically acceptable salts thereof are superior as the active ingredient of an antiallergic agent as discussed by the authors.
Abstract: The present invention provides a compound which is highly safe in terms of toxicity and has a stronger antiallergic action, and particularly has an action of inhibiting both immediate and delayed type allergic reactions. A benzopyran derivative represented by the general formula (I): wherein R1 is an alkyl group having 1-10 carbon atoms or an alkenyl group having 2-10 carbon atoms, and one of R2, R3, R4, and R5 is an alkoxy group substituted with a hydroxygroup or an alkoxy group substituted with a carboxy group, and the others are hydrogen atoms or physiologically acceptable salts thereof are superior as the active ingredient of an antiallergic agent.
2 citations