Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: X-ray crystal structures of 5b and a non-selective analog 5c in ERalpha help explain the observed selectivity of the benzopyran platform.
35 citations
TL;DR: In this paper, an anomalous reaction of a dibrominated chromone leading to a ring-opened product is described, which provides a method for the clean introduction of substituents into the chromone ring system.
Abstract: Activation of bromochromones has been achieved by Pd0 insertion into the carbon–halogen bond. The resultant species undergo coupling with alkenes leading to vinylated chromones. Vinylation occurs regiospecifically at the original site of bromination and therefore provides a method for the clean introduction of substituents into the chromone ring system. An anomalous reaction of a dibrominated chromone leading to a ring-opened product is described.
34 citations
TL;DR: In this paper, 4-heterocyclic substituted coumarin derivatives are screened for antiinflammatory activity in vitro through their antiproteolytic activity, the interaction with 1,1-diphenyl-2-picrylhydrazyl and the ability to affect superoxide anion and to inhibit β-glucuronidase and soybean lipoxygenase.
34 citations
TL;DR: The title compounds were obtained in good yields by [3, 3] sigmatropic rearrangement of 4 - [2-propynyloxy] coumarin and 3- [2propyny-loxy]-coumarin respectively.
33 citations
TL;DR: Five new flavagline derivatives were isolated from the leaves of Aglaia foveolata collected in Indonesia and has an unprecedented cyclic amide moiety in its cyclopenta[b]benzopyran skeleton, while compound 6 is a novel benzo[ b]oxepine derivative in which the oxepine ring is cleaved.
33 citations