Benzopyran

About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.

Amino-acid ester derivatives of 2h-chromen-5-ol

Abstract: CERTAIN AMINO ACID ESTER DERIVATIVES AND THEIR ACID ADDITON SALTS WHICH HAVE ANTI-DEPRESSENT AND ANTI-ANXIETY PROPERTIES. THE AMINO ACID ESTER GROUP IS AN ESTERIFIED 5OH PYRIDYL BENZOPYRAN.

Novel 4h-1-benzopyran-4-on derivative

Abstract: NEW MATERIAL: A compound of formula I (R1 is H, a 1-6C alkyl, a 3-6C cycloalkyl, etc.; R2 is H, a 1-6C alkyl, an aryl, etc.; R3 is H, a 1-4C alkyl, hydroxyl, etc.; R4 is H, hydroxyl, a 1-4C alkoxy, etc.; R5 is H, a 1-6C alkyl, a 3-6C cycloalkyl, etc.; (m) is 0-3; (n) is 0-2) and an acid-added salt thereof. EXAMPLE: (±)-cis-5,7-dihydroxy-2-(2-thienyl)-8-[4-(3-hydroxy-1-methyl)piperidinyl]-4 H-1-benzopyran-4-one. USE: Antitumor agent, inhibiting kinase or growth factor receptor tyrosine kinase for which oncogene codes. PREPARATION: A compound of formula II is reacted with an alkali metal and an alkyl ester to form the corresponding diketone of formula III, which, in turn, is cyclized by reaction with a mineral acid to obtain the objective compound of formula I.

Structure of visnagin, 4-methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one

Abstract: C 13H1004, M r = 230.22, orthorhombic, P2,2121, a = 7.0870 (6), b = 9.917 (1), c = 14.884 (2) A, V = 1046 (1) A 3, D x = 1.462 Mg m -3 for Z = 4, # = 0.118 mm -1, F(000) = 480, T = 294 K, diffractometer data, 2(Mo Ka) = 0.71069 A, 1109 data, 817 with I > 3a(/), R =0 .031 . The furobenzopyranone skeleton of the molecule is planar with r.m.s. deviation 0 .032A. The methoxy methyl group is 1.16 A out of plane. There are no short intermolecular

8,8-Dimethyl-8,9-dihydro-7H-chromeno[2,3-b]quinoline-10,12-dione.

Abstract: In the title compound, C18H15NO3, the fused benzopyran and pyridine rings are essentially coplanar [r.m.s. deviation = 0.0533 A with a maximum deviation of 0.080 (1) A for a benzene C atom]. The cyclo­hexa­none ring adopts an envelope conformation with the dimethyl-substituted C atom 0.660 (2) A out of the plane formed by the remaining ring atoms (r.m.s. deviation = 0.0305 A). The dihedral angle between the mean planes of the pyran and cyclo­hexa­none rings is 12.95 (6)°. In the crystal, mol­ecules are linked via C—H⋯O hydrogen bonds, leading to chains running along [011].