Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: In this paper, a novel intramolecular cyclisation reaction between an organocobalt stabilised cation and a trisubstituted alkene was accomplished to afford a new family of benzopyran derivatives.
28 citations
TL;DR: In this paper, the synthesis of pentacyclic benzopyran-annulated thiopyrano[2,3-b ] thiochromen-5(4 H )-ones has been described.
28 citations
TL;DR: The in vitro activities of the obtained euryfurylquinones and hydroquinones against Leishmania amazonensis are described and one of these Michael adducts undergoes a facile stereoselective cyclisation under oxidant conditions to afford a naphthofuro[4,3-c]benzopyran derivative.
28 citations
TL;DR: Of the seven compounds evaluated for antiproliferative activities, 3k and 3r were the most active, inhibiting leukaemia K562 cell proliferation by 50% after 72 h at concentrations of 4.5 and 7.9 mu M, whereas normal peripheral blood mononuclear cells were not affected.
28 citations
Patent•
24 Jun 1988
TL;DR: In this paper, novel benzopyrans having pharmacological activity, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension are presented.
Abstract: Disclosed herein are novel benzopyrans having pharmacological activity, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension.
27 citations