Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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Patent•
15 Oct 1996
TL;DR: In this article, the present invention relates to EI-1941 compounds having interleukin-1 production inhibitory activity which are represented by the formula: where either of R 1 and R 2 is hydrogen and the other one is hydroxy, or both of them are oxygen and hydrogen, respectively.
Abstract: The present invention relates to EI-1941 compounds having interleukin-1 production inhibitory activity which are represented by the formula:
wherein either of R 1 and R 2 is hydrogen and the other is hydroxy, or R 1 and R 2 together represent oxygen; and R 3 is hydroxy and R 4 is hydrogen, or R 3 and R 4 together represent -O-.
Patent•
08 Aug 2002
TL;DR: A first process for producing a benzopyran carboxamide represented by the general formula [1] includes reacting 3-aminopropionitrile with a base, and then reacting the reaction with the carboxylic halide to produce the benzoprinamide.
Abstract: A first process for producing a benzopyran carboxamide represented by the general formula [1] includes reacting 3-aminopropionitrile.½ sulfate, N≡CCH 2 CH 2 NH 2 .½(H 2 SO 4 ), with a benzopyran carboxylic halide represented by the general formula [2], in the presence of a base. A second process for producing the benzopyran carboxamide includes the steps of (a) reacting 3-aminopropionitrile.½ sulfate with a base, thereby forming 3-aminopropionitrile; and (b) reacting the 3-aminopropionitrile with the benzopyran carboxylic halide [2], thereby producing the benzopyran carboxamide. A process for stabilizing 3-aminopropionitrile includes turning the 3-aminopropionitrile into a sulfate of the 3-aminopropionitrile. where R is a straight-chain or non-straight-chain perfluoroalkyl group represented by C n F 2n+1 where n is an integer of 1-10; and X is fluorine, chlorine, bromine or iodine.
TL;DR: In this article, a regioselective method was developed for synthesis of substituted spiro(s) having one or two hydroxyl groups on the benzene ring.
Abstract: We have developed a novel regioselective method for synthesis of substituted spiro([1]benzopyran-2,4'-(1'H)pyrimidine)-2'-(3'H)thiones and spiro([1]benzopyran-2,4'-(1'H)pyrimidin)-2'-(3'H)ones having one or two hydroxyl groups on the benzene ring.
TL;DR: In this article, the coumarin system is essentially planar and the pyran ring adopts an envelope conformation, and there are intra-molecular C-H⋯O inter-actions and inter-Molecular π-π stacking interactions in the crystal structure.
Abstract: In the title compound, C25H30O4Si, the coumarin system is essentially planar and the pyran ring adopts an envelope conformation. There are intramolecular C—H⋯O interactions and intermolecular π-π stacking interactions in the crystal structure.
Patent•
13 May 1991
TL;DR: In this article, a diastereomer ester compound which is useful as an intermediate in the making of an optically active 3,4dihydro-3,4-epoxy-2H-1-benzopyran compound was presented.
Abstract: The present invention provides a new diastereomer ester compound which is useful as an intermediate in the making of an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound.