Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: The Micheal addition of ethyl 2-methoxy-, 2,4-dimethoxy- and 2,5-dimethylbenzoylacetates with benzoquinone leads to ethyl2-(rnethoxy or dimethoxy phenyl)-5-hydroxybenzofuran 3-carboxylates.
Abstract: The Micheal addition of ethyl 2-methoxy-, 2,4-dimethoxy- and 2,5-dimethoxybenzoylacetates with benzoquinone leads to ethyl 2-(rnethoxy or dimethoxy phenyl)-5-hydroxybenzofuran 3-carboxylates. Treatment of the henzofuran derivatives with anhydrous pyridine hydrochloride at 190–195° leads to hydroxy-6H-henzofuro[3,2-c] [1]benzopyran-6-ones.
Patent•
27 Oct 1993
TL;DR: A compound of the formula (I) is a compound in which: R 1 represents a hydrogen atom, a lower alkyl group, a hydroxy group or a lower alkoxy group, R 2, R 3, R 4, R 5, R 6, R 7, R 8 and R 11 are as defined in the description as discussed by the authors.
Abstract: A compound of the formula (I) ##STR1## in which: R 1 represents a hydrogen atom, a lower alkyl group, a hydroxy group or a lower alkoxy group, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 11 are as defined in the description. Medicaments.
Patent•
14 Jan 1993
TL;DR: In this article, the authors define a variant of the benzocycloalkane derivative of the formula wherein the ring A and the group Ar each may optionally have one or more substituents, with the proviso that compounds are excluded.
Abstract: Benzocycloalkane derivative of the formula wherein R is a hydrogen atom or a hydrocarbon residue, which may optionally have one or more substituents, Ar is an aromatic group, X is an oxygen or sulfur atom, l is 0 or 1, m is 3 to 6 and n is 0 to 2, wherein the ring A and the group Ar each may optionally have one or more substituents, with the proviso that compounds are excluded, wherein Ar is whereby Rx and Ry are independently selected from alkyl or alkoxy of from one to seven carbon atoms, or its pharmaceutically acceptable salt, which is useful as inhibitors for acyl-CoA : cholesterolacyltransferase.
Patent•
10 Apr 2003
TL;DR: In this paper, a secondary amine including tetrazole substituted benzopyran derivatives, their preparation and pharmaceutical compositions containing them are described. But their use is limited to the treatment of neurons and brain injury.
Abstract: 本发明涉及用包括四唑的仲胺取代的苯并吡喃衍生物，其制备方法以及含有它们的药物组合物。 The present invention relates to a secondary amine including tetrazole substituted benzopyran derivatives, their preparation and pharmaceutical compositions containing them. 本发明的化合物可以用于保护神经元细胞和大脑损伤；抗氧化；抑制NO产生；保护心脏；抑制血管生成；保护保存的器官如肾、心脏和组织，并且在心血管大手术中保护器官。 The compounds of the invention can be used to protect neurons and brain injury; antioxidant; inhibition of NO production; protect the heart; inhibit angiogenesis; preservation and conservation of organs such as the kidney, heart and tissue and organ protection in cardiovascular major surgery.