Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: In this paper, the oxidative cyclization of vinylogous esters (I) bearing a para-methoxybenzyl group affords spirofuran derivatives.
Abstract: The oxidative cyclization of vinylogous esters (I) bearing a para-methoxybenzyl group affords spirofuran derivatives (II), whilst the cyclization of vinylogous esters (III) bearing a meta-methoxybenzyl group gives rise to benzopyran derivatives (IV) as a sole product, even in the case of compound (IIId) bearing both meta- and para-methoxybenzyl moieties.
TL;DR: In this paper, a series of dihydrobenzopyranyloxypropanolamines and dihydronzopranylethanolamines containing a nitroxy moiety was synthesized.
Abstract: A series of dihydrobenzopyranyloxypropanolamines and dihydrobenzopyranylethanolamines containing a nitroxy moiety was synthesized. The cardiovascular effects of these compounds were investigated in anesthetized dogs. Some of the compounds exhibited hypotensive activity in combination with β-adrenergic blocking and vasodilating action. The structure-activity relationships are discussed.
Patent•
05 May 1988
TL;DR: Isoflavans of the formula I wherein the groups OR, R', R'' and ring B are as defined in the specification, exhibit valueable pharmacological properties, especially for the treatment of vascular diseases as mentioned in this paper.
Abstract: Isoflavans of the formula I wherein the groups OR, R', R'' and ring B are as defined in the specification, exhibit valueable pharmacological properties, especially for the treatment of vascular diseases. They are prepared by methods known per se.