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Benzopyran

About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.


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Patent
10 Sep 1986
TL;DR: In this paper, an o-allylphenol acetyl ester with an epoxidizing agent and cyclizing the obtained specific compound in the presence of an alkali halide, etc.
Abstract: PURPOSE:To obtain the titled substance useful as pharmaceuticals, etc., easily, without producing by-products, by reacting an o-allylphenol acetyl ester with an epoxidizing agent and cyclizing the obtained specific compound in the presence of an alkali halide, etc. CONSTITUTION:The compound of formula I (R is H, lower alkyl, lower alkoxy, halogen or nitro; n is 1-3; plural R groups may be same or different; R is lower acyl) is used as a raw material, and is made to react in the presence of an alkali halide or a quaternary ammonium halide, in a solvent (preferably acetone, etc.) at 50-120 deg.C under refluxing, and if necessary the product is deacylated to obtain the compound of formula II (R is H or acyl). The amount of the alkali halide or quaternary ammonium halide is preferably 0.1-1 mol- equivalent.
Journal ArticleDOI
TL;DR: In this article, a key step in their biogenesis may involve a hetero Diels-Alder cycloaddition between an o-quinone methide intermediate with a simple, or activated tri-substituted olefin.
Abstract: Lucidene and alboatrin are complex benzopyran derived natural products. A key step in their biogenesis may involve a hetero Diels–Alder cycloaddition between an o-quinone methide intermediate with a simple, or activated tri-substituted olefin. Experimental evidence is provided to support this hypothesis, with the biomimetic synthesis of both (±)-lucidene and (±)-alboatrin successfully achieved using a new and efficient method for o-quinone methide generation.
Journal ArticleDOI
TL;DR: The title process of as discussed by the authors is based on the initial formation of a reactive 1,1-diactivated alkene from dimedone or dimethylbarbituric acid and carbonyl compounds (II) followed by a intramolecular Wittig-type ring closure.
Abstract: The title process is based on the initial formation of a reactive 1,1-diactivated alkene from dimedone or dimethylbarbituric acid and carbonyl compounds (II) followed by a intramolecular Wittig-type ring closure.

Network Information
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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20234
202220
202114
20209
201925
201814