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Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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Patent•
04 May 2012
TL;DR: The benzopyran chalcone compound has a structure as described in the specification as discussed by the authors, which has inhibiting effects on inflammatory factors like iNOS, TNF-alpha and IL-4 and can be used for treating inflammations like osteoarthritis, rheumatoid arthritis and asthma.
Abstract: The invention relates to the fields of organic chemistry and pharmaceutical chemistry, specifically to a benzopyran chalcone compound having anti-inflammatory activity and a preparation method and application thereof. The benzopyran chalcone compound has a structure as described in the specification. According to results of experiments, the compound has inhibiting effects on inflammatory factors like iNOS, TNF-alpha and IL-4 and can be used for treating inflammations like osteoarthritis, rheumatoid arthritis and asthma.
TL;DR: In this paper, it was shown that the bond between the spiro carbon atom and the oxygen heteroatom of the pyran ring is not broken during the formation of the radical-anion and its subsequent protonation and that the unpaired electron is delocalized in the π system of the benzopyran fragment of the molecule.
Abstract: Calculations by the extended Huckel iteration method with self-consistency with respect to the charges were undertaken for the initial molecule, the radicalanion, and the neutral radical formed during protonation of the latter in 1,3,3-trimethylspiro[indoline-2,2′-(2′H)-chromene]. On the basis of the results from the calculations and analysis of the ESR spectrum of the neutral radical it was concluded that the bond between the spiro carbon atom and the oxygen heteroatom of the pyran ring is not broken during the formation of the radical-anion and its subsequent protonation and that the unpaired electron is delocalized in the π system of the benzopyran fragment of the molecule. Protonation in the radicalanion takes place at the carbon atom at position 3′.
TL;DR: In this article, the litterature correspondant au volume 103 des Chemical Abstracts is couvrant les litteratures correspondant correspondant to le volume 3, 5, 6, 7, 8, 9, 10, 11, 12,
Abstract: Article de synthese couvrant la litterature correspondant au volume 103 des Chemical Abstracts
TL;DR: In this paper, a rapid, solvent-free and environmentally friendly Knoevenagel condensation reaction of 4-oxo-(4H)-1-bcnzopyran-3-carbaldehyde with Meldrum's acid has been carried out under microwave irradiation.
Abstract: A rapid, solvent-free and environmentally friendly Knoevenagel condensation reaction of 4-oxo-(4H)-1-bcnzopyran-3-carbaldehyde 1 with Meldrum's acid 2 has been carried out under microwave irradiation. The structures of condensed products 3a-g have been characterized on the basis of IR and 1 H NMR spectral data.