Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
Papers published on a yearly basis
Papers
More filters
Patent•
17 Aug 1993
TL;DR: In this paper, the use of benzopyran and benzoxazine derivatives represented by general formula (I) and the use thereof as a K+ channel activator for treating asthma, epilepsy and so forth, wherein R?1? and R2 represent each lower haloalkyl; R3 represents hydrogen, etc.
Abstract: Benzopyran and benzoxazine derivatives represented by general formula (I) and the use thereof as a K+ channel activator for treating asthma, epilepsy and so forth, wherein R?1? and R2 represent each lower haloalkyl; R3 represents hydrogen, etc.; R4 represents a heterocyclic group, A-O- (A being a ring structure), etc.; R5 and R6 represent each lower haloalkyl; and X represents =N-, N->O or (II) (R7 and R8 being each hydrogen, hydroxyl, etc.).
17 citations
TL;DR: Hirtellanine A was assembled using a tandem acid-mediated deprotection and tautomerization cascade starting from quinone derivative 23 as mentioned in this paper, and the key features of the synthesis include a Houben-Hoesch reaction of aryl cyanide 3 with phloroglucinol, a one-pot sequential boronation, a Suzuki-Miyaura cross-coupling, and a base-mediated regioselective Claisen rearrangement for the benzopyran construction.
17 citations
TL;DR: The title aldehyde as mentioned in this paper reacts smoothly with the enamine moiety of 2-aminochromone to produce hitherto unreported 3-(2-hydroxybenzoyl)-5H-1-benzopyrano[2,3-b]pyridin-5-one (azaxanthone) 5.
17 citations
Patent•
21 May 2007TL;DR: In this paper, a process for the production of a compound of formula (I), where Y is selected from CH3, CH2OH, CH 2CH2OH and CH2Br, is described.
Abstract: The invention provides a process for the production of a compound of formula (I), wherein Y is selected from CH3, CH2OH, CH2CH2OH, CH2Br and Br; comprising the steps of: (i) reacting a compound of formula (II), wherein OX is hydroxy or O- M+, in which M+ is a cation selected from Li+, Na+ and K+, and Y is as defined above; with trans-cinnamaldehyde (III), in the presence of a secondary amine compound; then (ii) treating the product of the preceding step with acid to afford the compound of formula (I). The above process may be used in the production of tolterodine and fesoterodine, which are useful in the treatment of overactive bladder.
17 citations
TL;DR: The reaction of substituted cinnamonitriles with 4-hydroxycoumarin in water in the presence of triethylbenzyl-ammonium chloride affords 2amino-4-aryl-4H,5H-pyrano [3,2-c] [1]benzopyran-5-one deriv...
Abstract: The reaction of substituted cinnamonitriles with 4-hydroxycoumarin in water in the presence of triethylbenzyl-ammonium chloride affords 2-amino-4-aryl-4H,5H-pyrano [3,2-c] [1]benzopyran-5-one deriv...
17 citations