Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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01 Jan 1987
TL;DR: A series of diHydrobenzopyranyloxypropanolamines and dihydrobenZopyranylethanolamines containing a nitroxy moiety was synthesized and the cardiovascular effects of these compounds were investigated in anesthetized dogs.
Abstract: Synthese et etude biologique d'une serie de chromannyloxy-1 amino-3 propanols-2 et de [chromannyl-8]-1 ethanolamines
13 citations
Patent•
12 May 1993TL;DR: In this article, the authors present a list of compounds having the formula "STR1##" and pharmaceutically acceptable salts thereof, which have potassium channel activating activity and are useful for example, as cardiovascular agents.
Abstract: Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof. These compounds have potassium channel activating activity and are useful, therefore for example, as cardiovascular agents.
13 citations
TL;DR: In this article, the alkyl chain substituted spiropyran derivatives, 1-methyl-3,3-dimethyl-6‘-nitrospiro[indoline-2,2']-2H][1]benzopyran] (SP1), 1-octadecyl-3.3dimethyl6']-nitro-8-[docosanoyloxymethyl]spiro [indoline]-2, 2']-
Abstract: We incorporated the alkyl chain substituted spiropyran derivatives, 1-methyl-3,3-dimethyl-6‘-nitrospiro[indoline-2,2‘-[2H][1]benzopyran] (SP1), 1-octadecyl-3,3-dimethyl-6‘-nitrospiro[indoline-2,2‘-[2H][1]benzopyran] (SP18), and 1-octadecyl-3,3-dimethyl-6‘-nitro-8-[docosanoyloxymethyl]spiro[indoline-2,2‘-[2H][1]benzopyran] (SP1822) into the planar bilayer lipid membranes (BLM) of soybean lecithin for the first time, and the photoresponse of the BLM was monitored. When a dc voltage was applied across the BLM, the transmembrane current changed under alternate irradiation with ultraviolet light and visible light. Such a photoelectric response of the BLM seems to be caused by the change in the membrane conductivity due to photoisomerization of spiropyran.
13 citations
Journal Article•
13 citations
TL;DR: A series of optically active tetrahydro-oxazino[2,3-c]benzopyran derivatives have been synthesized and evaluated for potassium channel opening activity and 9-carb onitrile was identified as a bladder-selective potassium channel opener.
13 citations