Benzopyran

About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.

A comparison of electron impact mass spectrometry of isomeric pyranocoumarins (pyrano[3,2‐c][1]benzopyran‐5‐ones) and pyranochromones (pyrano[2,3‐b][1]benzopyran‐5‐ones)

Abstract: The mass spectrometric behaviour of two pairs of isomeric 2,2-dimethylpyrano[3,2-c][1]benzopyran-5-ones (pyranocoumarins) and 2,2-dimethylpyrano[2,3-b][1]benzopyran-5-ones (pyranochromones) and four pairs of isomeric 2-hydroxymethyl-2-methylpyrano[3,2-c][1]benzopyran-5-ones (pyranocoumarins) and 2-hydroxymethyl-2-methylpyrano[2,3-b][1] benzopyran-5-ones (pyranochromones) has been studied in detail with the aid of exact mass measurements, linked scans, collisionally activated decompositions and deuterium labelling experiments. The presence in both series of compounds of the same ions derived by structural interconversion of both molecular ions is emphasized, and structural information on the ions [C7H5O2]+ (m/z 121), highly characteristic for these classes of compounds, as for 4-hydroxycoumarins, is reported.

A review of benzopyran derivatives in pharmacotherapy of breast cancer

Abstract: One of the naturally occurring compounds containing oxygen moiety is benzopyran. Depending on its substitution pattern, different biological effects are shown. The benzopyran ring system is present in many natural products (such as genistein, hesperidin, and warfarin) as well as synthetic products. It displays pharmacological properties such as antitumor, anti-HIV, antimicrobials, anti-inflammatory, and anticoagulants. The sufficient literature support and the fact that benzopyran has potential as a pharmacophore particularly as anti-breast cancer, etc, current research seemed pertinent keeping in view the mechanism of anti-breast cancer activity. Therefore, the objective of this review is to focus on important benzopyran analogs with anti-breast cancer activity and highlight their mechanisms of action.

Isoflavone compound, its preparation method, and its application in preparation of antiviral or antitumor drugs

Abstract: The invention relates to an isoflavone compound, its preparation method, and its application in the preparation of antiviral or antitumor drugs, and concretely relates to a compound with a structural formula represented by formula (I). In the formula (I), R1 is hydrogen or C1-6 alkyl; X is -O-, -NH-, -CH=CH-, or ethinyl, or R2 is directly connected with benzopyran; R2 is selected from substituted or unsubstituted phenyl, substituted or unsubstituted heteroaryl, C1-16 alkyl, C1-16 alkyloxy, C1-16 alkyloxycarbonyl, or substituted or unsubstituted benzoyloxy; the heteroaryl is selected from groups derived from a five or six-membered heterocycle or a fused heterocycle containing one or two hetero atoms of N, O or S, and is selected but not limited to pyridyl, benzopyridyl, or groups derived from phenoxathiin, thiophene, oxazole and benzopyridine; and above substituent is selected from halogen, cyan, nitro, hydroxy, amino, C1-6 monosubstituted or disubstituted amino, C1-16 alkyl, halogenated C1-6 alkyl, C2-6 alkenyl, C6-12 arylalkenyl, C1-16 alkyloxy, C1-16 carboxyl, C1-16 alkyloxycarbonyl, C1-16 alkylcarbonyl, and substituted or unsubstituted phenoxyl. The invention also provides the preparation of the compound.

Green and practical synthesis of benzopyran and 3-sunstituted coumarin derivatives by Brønsted acid ionic liquid [(CH 2 ) 4 SO 3 HMIM][HSO 4 ]

Abstract: Different benzopyran and 3-substituted coumarin derivatives were synthesized by a green and practical procedure in the presence of catalytic amount of Bronsted acid ionic liquid (BAIL) [(CH 2 ) 4 SO 3 HMIM][HSO 4 ] in water. KEY WORDS : Benzopyran derivatives, 3-Substituted coumarin derivatives, Bronsted acid ionic liquid, 1-(4-Sulfonic acid)butyl-3-methylimidazolium hydrogen sulfate Bull. Chem. Soc. Ethiop. 2011 , 25(2), 315-320.