Showing papers on "Benzopyrans published in 1974"

[Pyrrolidine-3 and pyrazoline-4-spiro-1'-isothiochromanes and -isochromanes. 12. Studies on the isochromane- and isothiochromane series].

Abstract: Aus 1‐Cyan‐isothiochroman bzw. ‐isochroman sind durch Umsetzung mit Chloracetonitril 1‐Cyan‐1‐cyanmethyl‐isothiochroman (1a) bzw. ‐isochroman (1c) zugänglich, die sich durch Verseifung in 2,5‐Dioxo‐pyrrolidin‐(3‐spiro‐1′)‐isothiochroman (2a) bzw. ‐isochroman (2c) überführen lassen. – 1‐Cyan‐isothiochroman‐1‐carbonsäuremethylester (4) und Hydrazin können zu 3‐Amino‐5‐oxo‐pyrazolin‐ bzw. 3‐Imino‐5‐oxo‐pyrazolidin‐(4‐spiro‐ 1′)‐isothiochroman (6 bzw. 5) kondensiert werden.

Des-A steroidal intermediates

Abstract: Stereo-specific total synthesis of steroidal materials. 7Substituted 3-oxo-1-heptenes or variants thereof are reacted with 2-alkylcycloalkane-1,3-diones yielding 3-substituted 6a Beta alkyl-cyclopenta (f)(1)benzopyrans or naphtho (2,1-b)pyrans. These are then subjected to a selective catalytic hydrogenation followed by an introduction of a hydroxy, alkoxy or acyloxy group at the 4a-position to produce a 3-substituted 6a Beta ,4ahydroxy, alkoxy or acyloxy perhydrocyclopenta (f)(1)benzopyran or perhydro-naphtho (2,1-b) pyran. These latter compounds are then converted into 4- or 5-(3-oxoalkyl)perhydroindene-5-ones or perhydronaphthalene-6-ones which in turn can be converted to known steroidal materials by known methods.

Alkyl substituted cyclopenta benzopyrans

Abstract: of the Disclosure 1,2,3,4-Tetrahydrocyclopenta[c][l]benzopyrans of the formulae and wherein R is a lower alkyl group having 1 to 5 carbons, R1 is hydrogen or a lower alkyl group having 1 to 5 carbons, R2 is a lower alkyl group and R3 is an alkyl group having 1 to 20 carbon atoms, a phenyl-lower alkyl group or a cycloalkyl-lower alkyl group. The compounds have anti-hypertensive, antidepressant, analgesic, anticonvulsant, anti-anxiety and tranquilizing activity in animals.

Synthesis of 3-(p-methoxyphenyl)-1, 3-dimethylspiro (indoline-2,2′- [2H-1]-benzopyrans) and investigation of the electronic absorption spectra of their merocyanine forms

Abstract: Photochromic indoline spiropyrans containing a p-methoxyphenyl substituent in the 3-position were synthesized, and the electronic absorption spectra of their merocyanine forms were measured.

Benzopyrans and intermediates for the preparation of pyrrolo benzopyrans

Abstract: Novel 7-alkyl-(and 7-cycloalkyl-loweralkyl)9-hydroxy-4,4-di-lower-alkyl-1,2,3,4-tetrahydro-[1]benzopyrano[3,4-c]pyrroles; 7-alkyl-(and 7-cycloalkyl-lower-alkyl)9-hydroxy-4,4-di-lower alkyl-1,2,3,4,3a,9b-hexahydro[1]benzopyrano[3,4-c]pyrroles, and certain ester and ether derivatives thereof. These compounds exhibit CNS activity, and are useful as sedatives or tranquilizers.