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Benzopyrans
About: Benzopyrans is a research topic. Over the lifetime, 694 publications have been published within this topic receiving 8830 citations.
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TL;DR: The enamine (2) as discussed by the authors is a mixture of benzopyranone and dimethylformamide dimethyl acetal and on treatment with ammonia and hydroxylamine gives the fused pyridine 2-oxide (10), pyridinioacetamidate (11), and azepine (20), respectively.
Abstract: The enamine (2), prepared from the title benzopyranone (1; R2= H, Me, and Ph) and dimethylformamide dimethyl acetal, on treatment with ammonia and hydroxylamine gives the fused pyridine (5) and pyridine 2-oxide (10), respectively. Hydrazine, phenylhydrazine, and guanidine undergo initial 1,6-addition to the enamine (2) ultimately giving the pyrazoles (14) and (15), and the pyrimidine (17), respectively. The pyridinioacetamidate (11), prepared from the enamine (2; R2= Me and Ph) and acetohydrazide, thermolyses to the fused pyridine (5). A refluxing ethanolic solution of the enamine (2; R2= Me and Ph) with ethyl glycinate forms the ester (18) which on treatment with ethanolic sodium ethoxide produces the azepine (20).