Topic
Benzopyrans
About: Benzopyrans is a research topic. Over the lifetime, 694 publications have been published within this topic receiving 8830 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: A series of 3-nitro-2-phenyl-2H-1-benzopyrans (3a-h) were prepared and treated with diazomethane and diazoethane to give various benzopyranopyrazole derivatives as discussed by the authors.
Abstract: A series of 3-nitro-2-phenyl-2H-1-benzopyrans (3a-h) were prepared and treated with diazomethane and diazoethane to give various benzopyranopyrazole derivatives namely [1,9-b]dihydro-3a- nitro-4-phenyl[1]benzopyrano[3,4-c]pyrazolines(4a-h), 4-phenyl[1]benzopyrano [3,4-c]pyrazoles (5a-h) and [1,9-b]dihydro-1-methyl-3a-nitro-4-phenyl[1]benzopyrano[3,4-c]pyrazolines (6a-h) respectively. The regio and stereochemical outcome of these cycloadditions are discussed. The benzopyranopyrazole derivatives 4a-h and 6-ah were tested for their antimicrobial activities against S. aureus, S. lutea, B. subtilis, E. coli, S. typhosa, S. cerevesciae and C. albicans. Compounds 4a-h were found to be moderately active against the gram positive bacteria and the fungi that were tested.
•
19 Jun 2002
TL;DR: A method of treating atherosclerosis in a mammal, including a human, comprisingadministering to said mammal an amount of the compound of the formula or the pharmaceutically acceptable salt thereof, is described in this paper.
Abstract: A method of treating atherosclerosis in a mammal, including a human, comprising
administering to said mammal an amount of the compound of the formula
an enantiomer, or the pharmaceutically acceptable salt thereof;
effective to treat atherosclerosis, wherein R 1 , R 2 and R 3 are as defined herein.
••
TL;DR: In this paper, an unusual cyclocondensation of o-hydroxybenzaldehydes with 2,2-dimethoxypropane at ambient temperature was shown to produce 2,4-dimethyl-2-methyl-2H-1-benzopyrans in high yields with high diastereoselectivity.
Abstract: Iron(III) catalyses efficiently an unusual cyclocondensation of o-hydroxybenzaldehydes with 2,2-dimethoxypropane at ambient temperature to produce 2,4-dimethoxy-2-methyl-2H-1-benzopyrans in high yields with high diastereoselectivity. Also, it catalyses the formation of benzopyran derivatives from o-hydroxybenzaldehydes, acetone and trimethyl orthoformate. *IICT Communication No. 4675.
••
TL;DR: A microwave promoted novel protocol for the synthesis of diverse kinds of substituted benzopyrans from the corresponding variety of substituted hydroxy acetophenones and keto compounds using Amberlite IRA 400 resin (basic resin) under solvent-free conditions, has been developed as discussed by the authors.
Abstract: A convenient, microwave promoted novel protocol for the synthesis of diverse kinds of substituted benzopyrans from the corresponding variety of substituted hydroxy acetophenones and keto compounds using Amberlite IRA 400 resin (basic resin) under solvent-free conditions, has been developed. This protocol is mild and more efficient than the other reported methods.
••
TL;DR: In this paper, substitution to the alkoxy group enhances the reactivity of the substrates and leads to the higher yields of the corresponding products, and the substitutions can be found in the literature.
Abstract: ortho-Substitution to the alkoxy group enhances the reactivity of the substrates and leads to the higher yields of the corresponding products [cf.