Topic
Benzopyrans
About: Benzopyrans is a research topic. Over the lifetime, 694 publications have been published within this topic receiving 8830 citations.
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TL;DR: In this article, the synthesis and photochromic properties of 6,7- and 7,8-benzoindene annellated benzopyrans are described and compared to parent indeno-fused 2H-chromenes.
Abstract: The synthesis and the photochromic properties of new photochromic 6,7- and 7,8-benzoindene annellated benzopyrans are described. When compared to parent indeno-fused 2H-chromenes (2H-[1]benzopyrans), compounds 10 and 12 exhibit a significant bathochromic shift of maximum-absorption wavelength, an increase in the colorability, and similar fading rates.
21 citations
Patent•
05 Nov 1993TL;DR: A method of inhibiting bone loss comprising administering to an animal an effective amount of a compound having the formula ##STR1## wherein: R1 and R2 are, independently, --H, --OH, halo, --OC1 -C17 alkyl, OOC3 -C6 cycloalkyl, --O(CO)C 1 -C 17 alkyls, OCOA-O aryl, OROCO2 -(n-butyl or n-pentyl); R3 is ##STR2## R4 is --H
Abstract: A method of inhibiting bone loss comprising administering to an animal an effective amount of a compound having the formula ##STR1## wherein: R1 and R2 are, independently, --H, --OH, halo, --OC1 -C17 alkyl, --OC3 -C6 cycloalkyl, --O(CO)C1 -C17 alkyl, --O(CO) aryl, --O(CO)O aryl, or --OSO2 -(n-butyl or n-pentyl); R3 is ##STR2## R4 is --H, methyl, ethyl, propyl, ethenyl or ethynyl; or a pharmaceutically acceptable salt or solvate thereof.
20 citations
Patent•
06 Sep 1991TL;DR: In this article, the authors proposed a method of treating a viral infection using compounds represented by Formula 1.0: ##STR1## and their pharmaceutically acceptable salts and solvates, which are useful as antihypertensive agents and useful as antiviral agents against DNA-containing viruses.
Abstract: Compounds useful as antihypertensive agents and useful as antiviral agents against DNA-containing viruses, such as herpes group viruses, are disclosed. The compounds are represented by Formula 1.0: ##STR1## and their pharmaceutically acceptable salts and solvates. Pharmaceutical compositions containing compounds represented by Formula 1.0 are disclosed. Methods of treating a viral infection using compounds represented by Formula 1.0 are disclosed. Also disclosed are methods of treating hypertension using compounds of Formula 1.0 wherein R is selected from the group consisting of H, halogen and --C(O)OR6 ; and R1 is selected from the group consisting of --OR14, --O(CH2)a C(H)3-i Zi and --O(CH2)h N(R15)2.
20 citations
TL;DR: In this article, 1-Benzopyrans, such as chromans and chromenes, were prepared in good to excellent yields by using a catalytic amount of p-toluenesulfonic acid through intermolecular cyclization reaction of phenols with unsaturated alcohols in 1,2-dichlroroethane.
20 citations
Patent•
16 Nov 1981TL;DR: In this paper, the authors present methods of use for known pharmacological anti-allergenic agents including disodiumchromoglycate (DSCG) and related compounds thereof, including generally bis chromones, benzopyrans, oxamic acids and salts or esters of each, preferably lodoxamide, its THAM salt and ethyl ester.
Abstract: The present invention relates to novel methods of use for known pharmacological anti-allergenic agents including disodiumchromoglycate (DSCG) and related compounds thereof, including generally bis chromones, benzopyrans, oxamic acids and salts or esters of each, preferably lodoxamide, its THAM salt and ethyl ester. All are subsequently included in the term biologues. The methods are for the treatment of pathological cardiovascular ischemic states in animals, particularly humans. Additionally, novel compositions including the biologues of the present invention in combination with known vasodilators and feed stuffs are also disclosed.
19 citations