Topic
Benzopyrans
About: Benzopyrans is a research topic. Over the lifetime, 694 publications have been published within this topic receiving 8830 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this paper, 2.2-Iminocoumarin-3 carboxamides were recycled into 3-(1,1-dioxo-2H-benzo-1,2,4thiadiazinyl-3)coumarins under the Influence of o-aminobenzenesulfonamide.
Abstract: 2-Iminocoumarin-3-carboxamides recyclized into 3-(1,1-dioxo-2H-benzo-1,2,4-thiadiazinyl-3)coumarins under the Influence ofo-aminobenzenesulfonamide. An alternative method of synthesis is discussed. Proposed mechanisms for the recyclization are discussed.
10 citations
TL;DR: In this paper, a series of spiroindolinone compounds containing pyridine, pyrimidine, benzopyrans, pyrido, naphtodiazepines, pyrazole, and isoxazole ring systems were prepared via the reaction of 3-(2-oxo-2-(3-ox-3H-benzo[f]chromen-2-yl)ethylidene)indolin-2one (4) with an appropriate nucleophilic reagent.
10 citations
TL;DR: The antiproliferative activity of three benzopyrans isolated from the chloroform extract of the aerial parts of Hypericum polyanthemum was analysed in order to determine their effect on the growth and cell cycle in the U‐373 MG glioblastoma cell line.
Abstract: The antiproliferative activity of three benzopyrans isolated from the chloroform extract of the aerial parts of Hypericum polyanthemum was analysed in order to determine their effect on the growth and cell cycle in the U-373 MG glioblastoma cell line. Compound 1 was less cytotoxic than compounds 2 and 3. A synergistic effect was noticed when the three benzopyrans were used simultaneously. The cytotoxicity noted could be related to an arrest in G2/M phase, leading to apoptosis in the U-373 MG glioblastoma cell line.
10 citations
TL;DR: A palladium-catalyzed oxidative annulation/nucleophilic substitution sequence affording a library of alkenylated benzopyrans using 2-aryl-1,3-dicarbonyl compounds and allylic acetate is reported.
10 citations
TL;DR: In this paper, a new method for the synthesis of 3-(1,3,4-oxadiazol-2-yl)coumarins is proposed, which is based on the recyclization of 2-(N-aroylhydrazono) coumarin-3-carboxamides.
Abstract: A new method for the synthesis of 3-(1,3,4-oxadiazol-2-yl)coumarins is proposed. It is based on the recyclization of 2-(N-aroylhydrazono)coumarin-3-carboxamides, which are readily obtained by the reaction of 2-iminocoumarin-3-carboxamides with arenecarboxylic hydrazides in an acidic medium. Advantages of the given method over alternative synthetic schemes were shown. Proposals on the mechanism of reaction were made.
10 citations