Topic
Benzopyrans
About: Benzopyrans is a research topic. Over the lifetime, 694 publications have been published within this topic receiving 8830 citations.
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01 Jan 2002
TL;DR: In this article, the synthesis of enantiopure brominated and chlorinated phenolic lactaldehydes is described as well as an investigation into their cyclisation to form the corresponding 2-benzopyran-4,5-diols.
Abstract: The syntheses of enantiopure brominated and chlorinated phenolic lactaldehydes are described as well as an investigation into their cyclisation to form the corresponding 2-benzopyran-4,5-diols. It is found that the choice of halogen is important in these processes.
3 citations
Patent•
26 Aug 1985
TL;DR: There are provided benzopyrans of formula I, wherein the substituents, R5-R8 and EA are as defined in the specification as discussed by the authors.These compounds are useful as anti-asthmatic agents.
Abstract: There are provided benzopyrans of formula I, wherein the substituents, R5-R8 and EA are as defined in the specification. These compounds are useful as anti-asthmatic agents.
3 citations
TL;DR: In this article, the synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps.
Abstract: The synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps. The enantiomers of 8-hydroxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran 1b have been resolved. It is shown that the compound (−)-1b is a more selective D-2 agonist, compared to apomorphine.
3 citations
TL;DR: In this paper, the synthesis of 1-(6-hydroxy-4-methoxy-7,7-dimethyl-6,7dihydro-5H-furo[3,2g]chromen-5-yl) pyrrolidin-2-one (7) analogue to Cromakalim was described.
Abstract: We describe the synthesis of 1-(6-hydroxy-4-methoxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-5-yl) pyrrolidin-2-one (7) analogue to Cromakalim. Moreover, the synthesised furochromanone used to synthesise a fused heterocyclic compounds containing thiophene and coumarin rings via Gewald and Wittig reactions; respectively.
3 citations