Topic
Bicyclic molecule
About: Bicyclic molecule is a research topic. Over the lifetime, 29587 publications have been published within this topic receiving 451252 citations. The topic is also known as: bicyclic molecule.
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TL;DR: In this article, 1,2-Bis(2-methylbenzo[b]thiophen-3-yl)perfluorocylopentenes undergo photochromic reactions in which colouration/decolouration cycles can be repeated more than 104 times without significant loss of performance.
Abstract: 1,2-Bis(2-methylbenzo[b]thiophen-3-yl)perfluorocylopentenes undergo thermally irreversible photochromic reactions in which colouration/decolouration cycles can be repeated more than 104 times without significant loss of performance.
276 citations
273 citations
TL;DR: Exemples d'arylations intramoleculculeries d'arenes halogenes o-substitues par un groupe insature are given in this article.
Abstract: Exemples d'arylations intramoleculaires d'arenes halogenes o-substitues par un groupe insature
267 citations
TL;DR: The chemistry of bicyclic guanidinate anions is reviewed in light of recent advances in the synthesis of new derivatives, highlighting the potential for cross-stimulation of different areas.
266 citations
TL;DR: L-glutamic acid (15), prepared in five steps from 2-pivaloyl-7-deazaguanine, has been found to be an antitumor agent with its primary site of action at thymidylate synthase rather than purine synthesis.
Abstract: N-[4-[2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid (15), prepared in five steps from 2-pivaloyl-7-deazaguanine, has been found to be an antitumor agent with its primary site of action at thymidylate synthase rather than purine synthesis. This compound appears to be a promising candidate for clinical evaluation.
259 citations