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Bioprocess

About: Bioprocess is a research topic. Over the lifetime, 2219 publications have been published within this topic receiving 50972 citations.


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Journal ArticleDOI
TL;DR: Variation in cell capacitance showed the possibility of using this method as a means to indicate changes in the physiological state of cells during cultivation, which would be very useful in designing control strategies that would depend on the physiological states in the bioprocess.
Abstract: Measurement of capacitance, also referred to as dielectric permittivity, is a new method of estimating the concentration of cells, monitoring the growth and detecting the physiological changes during the cultivation of organisms in various bioprocess. Several types of biological cells were studied, namely; Saccharomyces cerevisiae, Escherichia coli, Perilla frutescens (plant cells) and AFP-27 hybridoma cells. Generally, a linear correlation between cell capacitance (C) and other biomass measurement technique such as optical density (OD) and dry weight (DW) was obtained using the different types of cell suspension. Therefore, this method could be used to monitor the growth of the organism during the active growth. It could be conveniently used to make a rapid estimate of the cell concentration such as in plant cell suspension culture. The capacitance sensor could also be designed to be installed and autoclaved in-situ in a bioreactor and used for on-line monitoring of cell growth. On the other hand, distinct deviations in the capacitance value were observed in relation with the growth stage of the organism. This was observed in all the organisms studied but the type of deviation depends on the physiology of the organism. This variation in cell capacitance showed the possibility of using this method as a means to indicate changes in the physiological state of cells during cultivation. This capability would be very useful in designing control strategies that would depend on the physiological states in the bioprocess.

60 citations

Journal ArticleDOI
TL;DR: By circumventing inhibiting product concentrations and thus intensifying aroma production, total yield of aroma compounds produced is higher in an IBP compared with batch cultivation and permeates obtained from pervaporation consist of highly enriched mixtures of produced flavors and fragrances.

60 citations

Journal ArticleDOI
TL;DR: Progress with the integration of amperometric and potentiometric biosensors into flow injection analysis (FIA) systems may provide a route to developing automated, reliable, on-line systems for bioprocess control.

60 citations

Book
01 Jan 1994
TL;DR: In this article, the development and regulation of Flavor, Fragrance, and Color Ingredients Produced by Biotechnology (C. Welsh), Development and Regulation of Flavor and Fragrance Production (F. Welsh and A. Manley), Aliphatic, Aromatic, and Lactone Compounds (D. Armstrong and L. Brown).
Abstract: Overview of Bioprocess Flavor and Fragrance Production (F. Welsh). Development and Regulation of Flavor, Fragrance, and Color Ingredients Produced by Biotechnology (C. Manley). Aliphatic, Aromatic, and Lactone Compounds (D. Armstrong and L. Brown). Fermentation Production of Pyrazines and Terpenoids for Flavors and Fragrances (E. Seitz). Savory Flavors (T. Nagodawithana). Dairy Flavors (D. Eaton). Production of Food Colorants by Fermentation (G. Jacobson and J. Wasileski). Plant Tissue Culture (O. Sahai). Genetic Engineering and Other Advanced Technologies (A. Gabelman). Index.

60 citations

Journal ArticleDOI
TL;DR: The article has opined, which organisms and what bioproducts should be the focus, while exploiting glycerol as feed, and a novel eco-biotechnological strategy employs metabolically diverse bacteria, which ensures higher reproducibility and economics.
Abstract: The biodiesel industry has the potential to meet the fuel requirements in the future. A few inherent lacunae of this bioprocess are the effluent, which is 10 % of the actual product, and the fact that it is 85 % glycerol along with a few impurities. Biological treatments of wastes have been known as a dependable and economical direction of overseeing them and bring some value added products as well. A novel eco-biotechnological strategy employs metabolically diverse bacteria, which ensures higher reproducibility and economics. In this article, we have opined, which organisms and what bioproducts should be the focus, while exploiting glycerol as feed.

60 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023331
2022785
2021165
2020153
2019159
2018127