Topic
Bioreactor
About: Bioreactor is a research topic. Over the lifetime, 9980 publications have been published within this topic receiving 192690 citations. The topic is also known as: bioreactors.
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TL;DR: Chlorophenol degradation was studied by combined anaerobic–aerobic treatments as a single or multi-substrate system and was found to be sequential: 2-Ch chlorophenol (2-CP) and 4-CP were degraded first, followed by 2,4,6-Trichlorophenols (2,4-6-TCP) while the contrary was obtained inAnaerobic degradation.
Abstract: Chlorophenol degradation was studied by combined anaerobic–aerobic treatments as a single or multi-substrate system. 2,4-Dichlorophenol (2,4-DCP) was degraded to the extent of 52 and 78% in up-flow anaerobic sludge blanket (UASB) and aerobic suspended growth (ASG) reactors respectively, at organic loading rates of 0.18 kg/m3/day and hydraulic retention time of 26.4 h in the presence of glucose. The UASB represents the dominating facultative anaerobic microbial population. When the effluent from the anaerobic reactor (UASB) was subjected to aerobic treatment on the ASG reactor, 2,4-DCP and COD removals of 86 and 95% respectively were achieved. Aerobic degradation of chlorophenol by acclimated mixed bacterial isolates was found to be sequential: 2-Chlorophenol (2-CP) and 4-CP were degraded first, followed by 2,4-DCP and 2,4,6-Trichlorophenol (2,4,6-TCP) while the contrary was obtained in anaerobic degradation. In anaerobic degradation by acclimated mixed bacterial cells, 2,4-DCP and 2,4,6-TCP were degraded first followed by mono-chlorophenols. The anaerobic/aerobic bioreactors were most efficient when operated in sequence (series) rather than in parallel.
79 citations
TL;DR: A bioreactor method recently scaled-up for manufacture of l -phenylalanine from cinnamic acid and ammonia achieves product titers of over 60 g/l and a raw material conversion of about 90%.
79 citations
ENEA1
TL;DR: The results confirms that at least the sulfonated aromatic amines formed under anaerobic conditions from the RO16 are recalcitrant to biodegradation and therefore aromaticAmines are still a matter of concern for the biological treatment of textile wastewater.
79 citations
TL;DR: Results obtained in this study indicate that large populations (10(4 to 10(7) CFU/g) of E coli O157:H7 survived for 36 days during composting in a bioreactor at an external temperature of 21 degrees C but were inactivated to undetectable levels after 7 to 14 days when the internal temperature of theBioreactor was 50 degrees C.
78 citations
TL;DR: It is demonstrated that culture in bioreactors at low oxygen tension favors the production and retention of GAG within cartilage matrix without adversely affecting chondrocyte proliferation or collagen deposition.
Abstract: Cartilage is exposed to low oxygen tension in vivo, suggesting culture in a low-oxygen environment as a strategy to enhance matrix deposition in tissue-engineered cartilage in vitro. To assess the effects of oxygen tension on cartilage matrix accumulation, porous polylactic acid constructs were dynamically seeded in a concentric cylinder bioreactor with bovine chondrocytes and cultured for 3 weeks at either 20 or 5% oxygen tension. Robust chondrocyte proliferation and matrix deposition were achieved. After 22 days in culture, constructs from bioreactors operated at either 20 or 5% oxygen saturation had similar chondrocyte densities and collagen content. During the first 12 days of culture, the matrix glycosaminoglycan (GAG) deposition rate was 19.5 × 10-9 mg/cell per day at 5% oxygen tension and 65% greater than the matrix GAG deposition rate at 20% oxygen tension. After 22 days of bioreactor culture, constructs at 5% oxygen contained 4.5 ± 0.3 mg of GAG per construct, nearly double the 2.5 ± 0.2 mg of GA...
78 citations