Topic
Bioreactor
About: Bioreactor is a research topic. Over the lifetime, 9980 publications have been published within this topic receiving 192690 citations. The topic is also known as: bioreactors.
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26 May 1987
TL;DR: In this paper, a bioreactor for anchorage or non-anchorage dependent cells or for immobilized enzymes that is capable of achieving high cell densities or concentrations of reaction products is disclosed.
Abstract: A bioreactor for anchorage or nonanchorage dependent cells or for immobilized enzymes that is capable of achieving high cell densities or concentrations of reaction products is disclosed. The bioreactor is capable of being easily scaled up. The bioreactor utilizes horizontal or radial flow of the culture or growth medium across a packed bed of microcarriers with attached cells or enzymes. The radial flow utilized by the chamber minimizes the non-optimal culture perfusion problems and maximizes the uniformity of medium delivery and cell and/or enzyme viability. The cell culture chamber possess the capability for the production of many industrially important and useful products, particularly in the medical, pharmaceutical, food, agricultural, environmental and purification industries. In the medical and pharmaceutical industries, the large scale production of therapeutically important substances such as anti-tumor factors, hormones, viral antigens, enzymes, interferons and other valuable biomolecules, is greatly facilitated.
76 citations
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TL;DR: Purple non-sulfur bacteria (PNSB) were cultivated by food industry wastewater in the anaerobic membrane photo-bioreactor and revealed the presence of Rhodopseudomonas palustris and significant changes in the photosynthetic bacterial community within the system.
76 citations
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TL;DR: The production rates and yields of L-lactic acid in both bioreactors appeared to be fairly well correlated with k(L)a (1/h), and the optimum culture conditions such as inoculum size, initial starch concentration, pH during the fermentation and aeration rate were determined.
75 citations
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TL;DR: Biological phenol degradation in a draft tube gas‐liquid‐solid fluidized bed (DTFB) bioreactor containing a mixed culture immobilized on spherical activated carbon particles was investigated, demonstrating the high treatment efficiency of using a DTFB.
Abstract: Biological phenol degradation in a draft tube gas-liquid-solid fluidized bed (DTFB) bioreactor containing a mixed culture immobilized on spherical activated carbon particles was investigated. The characteristics of biofilms including the biofilm dry density and thickness, the volumetric oxygen mass transfer coefficient, and the phenol removal rates under different operating conditions in the DTFB were evaluated. A phenol degradation rate as high as 18 kg/m3-day with an effluent phenol concentration less than 1 g/m3 was achieved, signifying the high treatment efficiency of using a DTFB.
75 citations
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TL;DR: Three bench-scale bioreactors were operated and the use of mites as fungal predators improved performance by increasing the overall mineralization of toluene to CO2, and by dislodging biomass along the bioreactor.
Abstract: Recent studies have focused on using vapor-phase bioreactors for the treatment of volatile organic compounds from contaminated air streams. Although high removal capacities have been achieved in many studies, long-term operation is often unstable at high pollutant loadings due to biomass accumulation and drying of the packing medium. In this study, three bench-scale bioreactors were operated to determine the effect of packing material and fungal predation on toluene removal efficiency and pressure drop. Toluene elimination capacities (mass toluene removed per unit packing per unit time) above 100 g m–3 h–1 were obtained in the fungal bioreactors packed with light-weight, artificial medium, and submersion of the packing in mineral medium once per week was found to provide sufficient moisture and nutrients to the biofilm. The use of mites as fungal predators improved performance by increasing the overall mineralization of toluene to CO2, and by dislodging biomass along the bioreactor.
75 citations