Topic
Bioreactor
About: Bioreactor is a research topic. Over the lifetime, 9980 publications have been published within this topic receiving 192690 citations. The topic is also known as: bioreactors.
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TL;DR: The first report on the dominance of candidate Saccharibacteria and on the examination of their metabolic behavior in a bioreactor treating real wastewater is reported, as a result of the low organic carbon availability that extendedly induced β-glucosidases to breakdown the least biodegradable organic fraction.
59 citations
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TL;DR: The development of a microfluidic bioreactor designed to facilitate the production of a single-dose of a therapeutic protein, in a small footprint device at the point-of-care, is described.
Abstract: Cell-free protein synthesis (CFPS) is a powerful technology that allows for optimization of protein production without maintenance of a living system. Integrated within micro and nanofluidic architectures, CFPS can be optimized for point-of-care use. Here, the development of a microfluidic bioreactor designed to facilitate the production of a single-dose of a therapeutic protein, in a small footprint device at the point-of-care, is described. This new design builds on the use of a long, serpentine channel bioreactor and is enhanced by integrating a nanofabricated membrane to allow exchange of materials between parallel "reactor" and "feeder" channels. This engineered membrane facilitates the exchange of metabolites, energy, and inhibitory species, and can be altered by plasma-enhanced chemical vapor deposition and atomic layer deposition to tune the exchange rate of small molecules. This allows for extended reaction times and improved yields. Further, the reaction product and higher molecular weight components of the transcription/translation machinery in the reactor channel can be retained. It has been shown that the microscale bioreactor design produces higher protein yields than conventional tube-based batch formats, and that product yields can be dramatically improved by facilitating small molecule exchange within the dual-channel bioreactor.
59 citations
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TL;DR: The adverse effects of salt on biological treatment of saline wastewater inoculated by activated sludge culture were investigated in this paper, where a synthetic wastewater composed of diluted molasses, urea, KH2PO4 and various concentrations of salt (1-5% w/v NaCl) was treated in an aerobic-biological reactor operating in fed-batch mode.
Abstract: The adverse effects of salt on biological treatment of saline wastewater inoculated by activated sludge culture were investigated. A synthetic wastewater composed of diluted molasses, urea, KH2PO4 and various concentrations of salt (1–5% w/v NaCl) was treated in an aerobic-biological reactor operating in fed-batch mode. An activated sludge culture obtained from a wastewater treatment plant was used as the seed. Variations of chemical oxygen demand (COD) removal rate and efficiency with salt concentration were determined. A rate expression including salt inhibition effect was proposed and kinetic constants were determined by using the experimental data. © 1997 SCI.
59 citations
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TL;DR: A novel overflow-type electrochemical membrane bioreactor without ion exchange membrane, was developed for wastewater treatment and utilized electricity recovered by microbial fuel cell (MFC) for membrane fouling mitigation in membraneBioreactor (MBR), showing great promise for practical wastewater treatment application.
59 citations
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TL;DR: Compared to MF, the FO process produced a better permeate quality in terms of nutrients, total organic carbon, as well as hydrophilic and biologically persistent trace organic chemicals (TrOCs), with no clear difference in the removal efficiencies between two processes.
59 citations