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Bioreactor

About: Bioreactor is a research topic. Over the lifetime, 9980 publications have been published within this topic receiving 192690 citations. The topic is also known as: bioreactors.


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Journal ArticleDOI
TL;DR: The results showed that GAC provided higher bacteria adsorption capacity, showed a more resistance to shock loading and allowed better operational control with respect to pressure drop than other inert carriers.

59 citations

Journal ArticleDOI
26 Oct 2018-Polymers
TL;DR: The purpose of this review is to summarize the bioreactor operations targeting high PHA productivity using pure cultures, including the utilization of lower-cost waste carbon substrates and atmospheric air as the aeration medium, as well as cultivation under non-sterile conditions.
Abstract: Microbial polyhydroxyalkanoates (PHAs) are promising biodegradable polymers that may alleviate some of the environmental burden of petroleum-derived polymers. The requirements for carbon substrates and energy for bioreactor operations are major factors contributing to the high production costs and environmental impact of PHAs. Improving the process productivity is an important aspect of cost reduction, which has been attempted using a variety of fed-batch, continuous, and semi-continuous bioreactor systems, with variable results. The purpose of this review is to summarize the bioreactor operations targeting high PHA productivity using pure cultures. The highest volumetric PHA productivity was reported more than 20 years ago for poly(3-hydroxybutryate) (PHB) production from sucrose (5.1 g L−1 h−1). In the time since, similar results have not been achieved on a scale of more than 100 L. More recently, a number fed-batch and semi-continuous (cyclic) bioreactor operation strategies have reported reasonably high productivities (1 g L−1 h−1 to 2 g L−1 h−1) under more realistic conditions for pilot or industrial-scale production, including the utilization of lower-cost waste carbon substrates and atmospheric air as the aeration medium, as well as cultivation under non-sterile conditions. Little development has occurred in the area of fully continuously fed bioreactor systems over the last eight years.

58 citations

Journal ArticleDOI
01 Nov 2015-Energy
TL;DR: Some changes occurred in the microbial communities of the anodic solutions when the MFCs were switched from fed- batch to continuous mode, while the differences were minor between different recirculation rates in fed-batch mode.

58 citations

Journal ArticleDOI
TL;DR: In this paper, the conditions in sequential batch reactor (SBR) are being set to develop and analyze the microbial community that opted for hydrogen production, and an optimum performance condition for a bioreactor was achieved after 40 days of operation.

58 citations

BookDOI
01 Jan 2014
TL;DR: The key drivers and accelerators which have made the journey of plant bioreactor industry successful are evaluated and thorough and rigorous analysis of these parameters may help the industry/academia to speed up the growth of plant bioactive industry for the production of bioactives.
Abstract: Bioactive compounds are the compounds having pharmacological or toxicological effects on humans and animals. At present, the bioactive compounds are categorized into two groups, secondary metabolites (originating from natural sources like plants, mammals, fungi, bacteria etc.) and therapeutic recombinant molecules (which are produced by using recombinant DNA technology in bacteria, mammals, plants etc.). Of the compounds produced from various sources, secondary metabolites produced from plants command highest market demand. Plants are also proved to be an ideal host system for the production of recombinant therapeutic molecules. Therefore, there has been a long pursuit for development of a technology which can provide high yielding plant based bioactive production system. An amalgam of plant cell culture and bioreactor technology was crucial in this direction. The plant bioreactor technology, so developed, has been put to the test many times for commercial scale production of plant bioactive molecules. There have been instances of success, but in general growth of plant bioreactor industry has been very slow. This chapter highlights various aspects of slow but successful growth of plant based bioactive production from culture vessel to bioreactor. We have evaluated the key drivers and accelerators which have made the journey of plant bioreactor industry successful. Speed breakers of this journey have also been discussed. Thorough and rigorous analysis of these parameters may help the industry/academia to speed up the growth of plant bioreactor industry for the production of bioactives.

58 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20241
2023726
20221,549
2021388
2020401
2019413