Topic
Bioreactor
About: Bioreactor is a research topic. Over the lifetime, 9980 publications have been published within this topic receiving 192690 citations. The topic is also known as: bioreactors.
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TL;DR: In this paper, two bench-scale completely mixed bioreactors were used to investigate the effect of potato-processing industrial wastewater on the acidogenesis of primary sludge and found that the addition of the starch-rich potato processing wastewater considerably improved the performance of the system, resulting in an increase in the net VFA and soluble chemical oxygen demand (COD) concentrations and corresponding specific production rates.
55 citations
TL;DR: A low pH sulfidogenic bioreactor, maintained at between pH 28 and pH 45, was used to remove sulfate from two extremely acidic (pH 13 to 30) synthetic mine waters that contained small amounts of ferrous iron, but no other chalcophilic metals as mentioned in this paper.
55 citations
TL;DR: A mathematical model to describe nutrient/growth factor transport and cell growth inside a microchannel bioreactor is presented and it is shown that the nature of spatial gradients in nutrient concentration can be controlled by both design and operating conditions and are a strong function of cell uptake rates.
Abstract: Recently developed perfusion micro-bioreac- torsofferthepromiseofmorephysiologicinvitrosystems for tissue engineering. Successful application of such bioreactors will require a method to characterize the bioreactor environment required to elicit desired cell function. We present a mathematical model to describe nutrient/growth factor transport and cell growth inside a microchannel bioreactor. Using the model, we first show that the nature of spatial gradients in nutrient concentra- tion can be controlled by both design and operating conditions and are a strong function of cell uptake rates. Next, we extend our model to investigate the spatial distributions of cell-secreted soluble autocrine/paracrine growth factors in the bioreactor. We show that the convective transport associated with the continuous cell culture and possible media recirculation can significantly alter the concentration distribution of the soluble signal- ing molecules as compared to static culture experiments and hence needs special attention when adapting static culture protocols for the bioreactor. Further, using an unsteady state model, we find that spatial gradients in nutrient/growth factor concentrations can bring about spatial variations in the cell density distribution inside the bioreactor,whichcanresultinloweredworkingvolumeof the bioreactor. Finally, we show that the nutrient and spatiallimitationscandramaticallyaffectthecomposition ofaco-culturedcellpopulation.Ourresultsaresignificant for the development, design, and optimization of novel micro-channel systems for tissue engineering. 2006 Wiley Periodicals, Inc.
55 citations
TL;DR: A municipal wastewater biosludge was acclimated to the degradation of 4-nitroaniline (4-NA), and batch tests showed, that 3-NA can serve as the sole source of carbon, nitrogen and energy.
55 citations
Patent•
21 Aug 1996
TL;DR: In this paper, a method and a system for the treatment of organic hazardous wastes from plant waste and associated wastewater treatment processes, whereby the waste is either introduced directly, or continuously separated from wastewater, and routed to a bioreactor, and whereby no organic solids are generated for further offsite disposal.
Abstract: A method and a system for the treatment of organic hazardous wastes from plant waste and associated wastewater treatment processes, whereby the waste is either introduced directly, or continuously separated from wastewater, and routed to a bioreactor, and whereby no organic solids are generated for further offsite disposal. The system disclosed includes a bioreactor (6) containing selected bacteria, untreated sludges, and recirculated biomass, and a liquid/solid separator (8) allowing water to be utilized elsewhere in the system and returning solids to the bioreactor. The biodegradation process, initiated continuously, converts hazardous organic constituents in waste stream and wastewater sludges from plant operations to inert materials, for extensive periods of operation, without the need for solids removal, external solids treatment or disposal.
55 citations