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Blood serum

About: Blood serum is a research topic. Over the lifetime, 46843 publications have been published within this topic receiving 993315 citations.


Papers
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Journal ArticleDOI
TL;DR: An investigation of the biochemical changes following experimental liver injury felt the need of a simple, rapid, and accurate method for determining the protein fractions in small amounts of serum and began with Kingsley’s biuret procedure.

15,717 citations

Journal ArticleDOI
TL;DR: The relatively low density of the lipoproteins was utilized by Lindgren, Elliott, and Gofman to separate them from the other serum proteins by ultracentrifugal flotation, and quantitation was subsequently performed by refractometric methods in the analytical ultracentRifuge.
Abstract: In the past few years several methods have been developed for the analysis of serum lipoproteins Lindgren, Elliott, and Gofman (1) have utilized the relatively low density of the lipoproteins to separate them from the other serum proteins by ultracentrifugal flotation Quantitation was subsequently performed by refractometric methods in the analytical ultracentrifuge Separations of lipoproteins have also been made by Cohn fractionation in cold ethanol, and the quantities of lipoprotein have been estimated from the lipid content of the fractions (2, 3) Widely used at the present time is the method of zone electrophoresis with quantitation either by staining (4) or by chemical analysis of eluates from the support

8,544 citations

Journal ArticleDOI
20 Aug 1976-Science
TL;DR: Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and low oxygen.
Abstract: Plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees C in RPMI 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and low oxygen (1 or 5 percent). The original parasite material, derived from an infected Aotus trivirgatus monkey, was diluted more than 100 million times by the addition of human erythrocytes at 3- or 4-day intervals. The parasites continued to reproduce in their normal asexual cycle of approximately 48 hours but were no longer highly synchronous. The have remained infective to Aotus.

7,496 citations

Book
01 Jan 1963
TL;DR: J.K. Kaneko, Serum Proteins and the Dysproteinemias, and M.H. Morris, The Vitamins.
Abstract: T.B. Farver, Concepts of Normality in Clinical Biochemistry. J.G. Hauge, DNA Technology in Diagnosis, Breeding, and Therapy. J.J. Kaneko, Carbohydrate Metabolism and Its Diseases. M.L. Bruss, Lipids and Ketones. J.J. Kaneko, Serum Proteins and the Dysproteinemias. L.J. Gershwin, Clinical Immunology. J.W. Harvey, The Erythrocyte: Physiology, Metabolism, and Biochemical Disorders. J.J. Kaneko, Porphyrins and the Porhyrias. J.E. Smith, Iron Metabolism and Its Disorders. W.J. Dodds, Hemostasis. J.G. Zinkl and M.B. Kabbur, Neutrophil Function. J.W. Kramer and W.E. Hoffmann, Clinical Enzymology. B.C. Tennant, Hepatic Function. D.F. Brobst, Pancreatic Function. W.E. Hornbuckle and B.C. Tennant, Gastrointestinal Function. G.H. Cardinet III, Skeletal Muscle Function. D.R. Finco, Kidney Function. G.P. Carlson, Fluid, Electrolyte, and Acid-Base Balance. J.A. Mol and A. Rijnberk, Pituitary Function. A. Rijnberk and J.A. Mol, Adrenocortical Function. J.J. Kaneko, Thyroid Function. L-E. Edqvist and M. Forsberg, Clinical Reproductive Endocrinology. T.J. Rosol and C.C. Capen, Calcium-Regulating Hormones and Diseases of Abnormal Mineral (Calcium, Phosphorus, Magnesium) Metabolism. R.B. Rucker and J.G. Morris, The Vitamins. M. Haskins and U. Giger, Lysosomal Storage Diseases. B.R. Madewell, Tumor Markers. C.S. Bailey and W. Vernau, Cerebrospinal Fluid. J.R. Turk and S.W. Casteel, Clinical Biochemistry in Toxicology. W.F. Loeb, Clinical Biochemistry of Laboratory Rodents and Rabbits. J.T. Lumeij, Avian Clinical Biochemistry. Appendixes. Index.

3,875 citations

Journal ArticleDOI
TL;DR: The results by this method agree very well with those obtained by electrophoresis and salt fractionation and the method is simple, it has excellent precision and the reagents are stable.

3,406 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20233
202225
2021953
20201,268
20191,757
20181,644