Topic
Boenninghausenia
About: Boenninghausenia is a research topic. Over the lifetime, 46 publications have been published within this topic receiving 382 citations.
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TL;DR: Bioassay guided fractionation of Boenninghausenia sessilicarpa resulted in the isolation of a new dimeric coumarin glucoside 9′-methoxyl rutarensin and a cytotoxic compound rutamarin, as well as an antivirus component leptodactylone, together with six known coumarins.
41 citations
TL;DR: Coumarin was evaluated against important forest insect pests and was active against Plecoptera reflexa, Clostera cupreata and Crypsiptya coclesalis at different concentrations varying from 1.0% to 5%.
Abstract: The leaves of Boenninghausenia albiflora afforded an insecticidal coumarin which was identified as murraxocin (7-methoxy-8-[1'-ethoxy-2'-hydroxy-3'-methyl-but-3'enyl]-coumarin) (1), on the basis of extensive 1- and 2-dimensional NMR experiments. This compound has previously been isolated from Murraya exotica but this is the first report of the full (1)H and (13)C data for this compound. This natural product was evaluated against important forest insect pests and was active against Plecoptera reflexa, Clostera cupreata and Crypsiptya coclesalis at different concentrations varying from 1.0% to 5% w/v. In the crude extract 70% mortality was observed, and for compound 1 80% mortality was observed at a concentration of 1.0% w/v. The percentage of insect mortality increased in a dose-dependent manner. Coumarins are poorly studied insecticides and there is potential to exploit this chemically simple group of natural products.
25 citations
TL;DR: From the methanolic extract of the leaves of Boenninghausenia albiflora MEISSNER var.
Abstract: From the methanolic extract of the leaves of Boenninghausenia albiflora MEISSNER var. japonica S. SUZUKI, a new coumarin, named matsukaze-lactone (I), C20H14O6, m.p. 267∼268°, was isolated. Methylation of I with dimethyl sulfate and methanolic alkali gave an acid (IIa), C22H22O8, which was oxidized to an acid (IIIa), C18H18O8. By decarboxylation of IIIa with copper powder, 2, 2', 4, 6'-tetramethoxybiphenyl (V) was obtained. From these results, the structural formula (Ia), (Ib) and (Ic) were proposed for matsukaze-Iactone.
25 citations
TL;DR: Various organic and aqueous extracts of aerial part of Boenninghausenia albiflora (Rutaceae) obtained by infusion and maceration were screened for their antimicrobial activity against eight animal and plant pathogenic bacteria using disc diffusion method.
Abstract: Various organic and aqueous extracts of aerial part of Boenninghausenia albiflora (Rutaceae) obtained by infusion and maceration were screened for their antimicrobial activity against eight animal and plant pathogenic bacteria (Bacillus subtilis, Staphylococcus aureus, Erwinia chrysanthemi, Escherichia coli, Proteus vulgaris, Xanthomonas phaseoli, Agrobacterium tumefaciens and Xanthomonas campestris) using disc diffusion method. Out of total 32 tests performed, 27 tests showed positive antibacterial activity at 1000 mg/ml concentration, whereas 15 instances exhibited zone of inhibition ³ 10 mm at same concentration. The activity shown by some of the extracts was found higher than ampicillin (10 mcg) and erythromycin (15 mcg), standard antibiotic used.
25 citations
TL;DR: The MeOH extracts of the ground part and the root of Boenninghausenia japonica NAKAI showed inhibitory activity against tumor cell growth and antiproliferative activity against human gastric adenocarcinoma, human uterus carcinoma, and murine melanoma cells were tested.
Abstract: The MeOH extracts of the ground part and the root of Boenninghausenia japonica NAKAI showed inhibitory activity against tumor cell growth. Fractionation of the extracts has resulted in isolation of 1,3-dihydroxy-4-(2'-hydroxy-3'-hydroxymethyl-3',4'-epoxy-butyl)-N-methylacridone, 1,3-dihydroxy-4-[(Z)-3'-hydroxy-3'-methyl-buten-1'-yl]-N-methylacridone, 3-(1',1'-dimethylallyl)-7-hydroxy-8-methoxy-2H-1-benzopyran-2-one, casegravol, cis-casegravol, and edgeworin in addition to 9 compounds reported from B. japonica and B. albiflora. The isolates from this plant and some related compounds were tested for antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.
23 citations