Showing papers on "Brucine published in 1989"
Patent•
28 Feb 1989
TL;DR: In this paper, a process for resolving (±)-cis-1-ethyl-1, 3, 4, 9-tetrahydro-4-(phenylmethyl)pyrano[3, 4-b]indole-1acetic acid (pemedolac) usinig brucine to obtain the corresponding (1S, 4R)-eutomer is useful as an analgesic
Abstract: This invention relates to a process for resolving (±)-cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indole-1-acetic acid (pemedolac) usinig brucine to obtain the corresponding (1S,4R)-eutomer Said eutomer is useful as an analgesic
2 citations
TL;DR: When phthaloyl-threo-DL-β-hydroxyleucine was resolved using brucine as a resolving agent, yellow and white crystals were obtained as discussed by the authors.
Abstract: When phthaloyl-threo-DL-β-hydroxyleucine was resolved using brucine as a resolving agent, yellow and white crystals were obtained. threo-L-Form was obtained from yellow crystals and threo-D-form from white ones. The appearance of yellow color is considered to be due to the stacking of benzene ring of phthaloyl group and of brucine molecule.