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Showing papers on "Brucine published in 1992"


Journal ArticleDOI
TL;DR: Of the compounds tested, only strychnine, brucine, taurine and (S)-HA-966 were more potent displacers of [3H]strychnines than of glycine binding.

31 citations


Journal ArticleDOI
TL;DR: Brucine (2,3-dimethoxystrychnidin1 O-one), an alkaloid originally isolated by Pelletier and Caventou in 1819 from the dry ripe seeds of Strychnos nux-vomica L. (Loganiaceae), has long been characterized as strychnine-like in regard to its pharmacologic and toxicologic effects but less potent than stryhnine (Sax and Lewis, 1989).

24 citations


Journal ArticleDOI
TL;DR: In this paper, high-quality gradient-selective COSY spectra were recorded at 300 MHz for brucine and gibberellic acid and double-quantum filtered gradient selective cosy spectra for Brucine, using a single-frequency, highresolution H-1 probe modified by the addition of an unshielded z-gradient coil set.
Abstract: High-quality gradient-selective COSY spectra were recorded at 300 MHz for brucine and gibberellic acid and double-quantum filtered gradient-selective COSY spectra for brucine, using a single-frequency, high-resolution H-1 probe modified by the addition of an unshielded z-gradient coil set. Data were efficiently recorded using buffered acquisition with a single transient per increment in t1 in times much lower than those required for phase-cycled COSY, and with no loss of information. Gradient-selective COSY90, COSY45 and long-range COSY45 experiments, and the correlations leading to chemical shift assignments for gibberellic acid, are reported.

12 citations


Journal Article
TL;DR: Two major indolic alkaloids, viz., strychnine ( 0.87%) and brucine (0.06%) contained in Strychnos nux- vomica L. seeds showed considerable change due to artificial inoculation with the spore suspensions of Aspergillus flavus.
Abstract: Two major indolic alkaloids, viz., strychnine (0.87%) and brucine (0.06%) contained in Strychnos nux- vomica L. seeds showed considerable change due to artificial inoculation with the spore suspensions of Aspergillus flavus Link: ex. Fries., A. niger van Teigh. and Penicillium citrinum Thorn. recorded as dominant fungal flora on the seeds during storage.

6 citations


Journal ArticleDOI
TL;DR: In this article, a new class of derivatives of α-cyanoacrylic acid, namely, its salts with brucine, tert-butyldimethylamine, and diisopropylmethylamines, were reported.
Abstract: Syntheses are reported for representatives of a new class of derivatives of α-cyanoacrylic acid, namely, its salts with brucine, tert-butyldimethylamine, and diisopropylmethylamine.

1 citations