Topic
Buffer solution
About: Buffer solution is a research topic. Over the lifetime, 6948 publications have been published within this topic receiving 112440 citations. The topic is also known as: pH buffer & buffer.
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TL;DR: The objective of this study was to measure the effects of long-term exposure of rat tail tendon fascicles to several concentrations of NaCl, sucrose, polyethylene glycol (PEG), and SPEG solutions on water content, solute diffusion, and mechanical properties.
39 citations
TL;DR: Glucose was electro-oxidized at -0.1 V vs. Ag/AgCl and at 1.5 mA cm(-2) current density in a physiological buffer solution at 37 degrees C to achieve high current density.
39 citations
TL;DR: In this article, a carbon-paste electrode modified with a newly synthesized Schiff base complex of cobalt was used for the determination of sub-micromolar amounts of methimazole.
Abstract: The electrochemical behavior of methimazole, as an antithyroid agent, is investigated on the surface of a carbon-paste electrode modified with a newly synthesized Schiff base complex of cobalt. The prepared modified electrode showed an efficient catalytic role in the electrochemical oxidation of methimazole, leading to remarkable decrease in oxidation overpotential and enhancement of the kinetics of the electrode reaction. The mechanism of the electrocatalytic process on the surface of the modified electrode is analyzed by obtaining the cyclic voltammograms in various potential sweep rates and pHs of the buffer solutions. The differential pulse voltammetry is applied as a very sensitive analytical method for the determination of sub-micromolar amounts of methimazole. A linear dynamic range of 1 � 10 � 6 to 1 � 10 � 4 M with a detection limit of 5 � 10 � 7 M is resulted for methimazole. The modified electrode is successfully applied for the accurate determination of methimazole in pharmaceutical and clinical preparations. The linear range in calibration curves remains constant in addition to tablet preparations of methimazole and also in spiking to the synthetic human serum samples. In comparison to calibration curves in background buffer solution, the slope of the curves showed a variation less than 3% in determinations in background solutions of tablet and human synthetic serum samples. These results showed high efficiency of the Voltammetric procedure for accurate determination of methimazole in drug and clinical preparations. The modified electrode can be prepared very easy and renewed in its surface by simple polishing. The reproducibility of the electrode response, based on ten measurements during two month, was 3.2% for the slope of the calibration curve.
39 citations
TL;DR: The results thus demonstrate that the surface structural unfolding was caused by the exposure of the protein molecule to the unsymmetrical energetic balance following surface adsorption.
Abstract: We have determined the structural conformations of human lactoferrin adsorbed at the air/water interface by neutron reflectivity (NR) and its solution structure by small angle neutron scattering (SANS). The neutron reflectivity measurements revealed a strong structural unfolding of the molecule when adsorbed at the interface from a pH 7 phosphate buffer solution (PBS with a total ionic strength at 4.5 mM) over a wide concentration range. Two distinct regions, a top dense layer of 15−20 A on the air side and a bottom diffuse layer of some 50 A into the aqueous subphase, characterized the unfolded interfacial layer. At a concentration around 1 g dm-3, close to the physiological concentration of lactoferrin in biological fluids, the adsorbed amount was 5.5 × 10-8 mol m-2 in the absence of NaCl, but the addition of 0.3 M NaCl reduced protein adsorption to 3.5 × 10-8 mol m-2. Although the polypeptide distributions at the interface remained similar, quantitative analysis showed that the addition of NaCl reduced...
39 citations
Patent•
15 Sep 2004TL;DR: In this paper, a composition and method using same for removing photoresist and/or processing residue from a substrate are described, which is essentially an acidic buffer solution having an acid selected from a carboxylic acid or a polybasic acid and an ammonium salt of the acid in a molar ratio of acid to ammonium, ranging from 10:1 to 1:10.
Abstract: A composition and method using same for removing photoresist and/or processing residue from a substrate are described herein. In one aspect, there is provided a composition for removing residue consisting essentially of: an acidic buffer solution having an acid selected from a carboxylic acid or a polybasic acid and an ammonium salt of the acid in a molar ratio of acid to ammonium salt ranging from 10:1 to 1:10; an organic polar solvent that is miscible in all proportions in water; a fluoride, and water wherein the composition has a pH ranging from about 3 to about 7.
39 citations