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Calibration curve

About: Calibration curve is a research topic. Over the lifetime, 6552 publications have been published within this topic receiving 95128 citations.


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Journal ArticleDOI
TL;DR: The IntCal working group as discussed by the authors developed an updated and extended radiocarbon calibration curve, IntCal20, for Northern Hemisphere terrestrial samples from 0 to 55,000 cal yr BP.

30 citations

Journal ArticleDOI
TL;DR: In this paper, the dependence of the distribution ratio in a two-phase system containing the substance to be determined or a substance reacting with it, on the total concentration of the substance is analyzed.

30 citations

Journal ArticleDOI
TL;DR: A sensitive analytical method based on flameless atomic absorption spectrometry with Zeeman correction has been validated for the quantitative determination in human plasma of platinum originating from cisplatin in a liposomal source, SPI-77 and the results indicated that platinum from SPI- 77 mainly concentrates in plasma and that binding to and/or endocytosis in red blood cells is negligible.
Abstract: A sensitive analytical method based on flameless atomic absorption spectrometry with Zeeman correction has been validated for the quantitative determination in human plasma of platinum originating from cisplatin in a liposomal source, SPI-77. The performance of the method was acceptable over a sample concentration range of 0.125–1.25 μmol platinum/L and the lower limit of quantification was determined to be 1.25 μmol platinum/L in undiluted clinical samples. The performance data of the assay were investigated using both a calibration curve with carboplatin in plasma ultrafiltrate and diluted human plasma samples spiked with SPI-77. The recoveries, between-day and the within-day precisions of both methods of calibration were not significantly different allowing carboplatin ultrafiltrate calibration standards to be used to quantify platinum derived from SPI-77 in human plasma. Apparently, the liposomal formulation had no significant influence on the determination of platinum. The usefulness of the presented method was demonstrated in a phase I clinical and pharmacokinetic study. In addition, in vitro experiments were carried out to determine the distribution of SPI-77 in blood. The results indicated that platinum from SPI-77 mainly concentrates in plasma and that binding to and/or endocytosis in red blood cells is negligible.

30 citations

Journal ArticleDOI
15 Jan 2008-Talanta
TL;DR: A novel and selective procedure for the determination of l- Cysteine and l-cystine based on vapour-generation Fourier transform infrared spectrometry is described and results obtained for real samples compared well with those obtained by a reference spectrometric method.

30 citations

Journal ArticleDOI
10 Aug 2018-Sensors
TL;DR: A novel method called laser-induced breakdown spectroscopy (LIBS) offering the advantages of no sample preparation, being nearly nondestructive and having a fast speed was applied for the analysis of metal contamination, showing that LIBS could be a promising method for accurate direct online quantification ofMetal contamination in insulators.
Abstract: The fast detection of classical contaminants and their distribution on high-voltage transmission line insulators is essential for ensuring the safe operation of the power grid. The analysis of existing insulator contamination has traditionally relied on taking samples during a power cut, taking the samples back to the lab and then testing them with elemental analysis equipment, especially for sugars, bird droppings, and heavy metal particulates, which cannot be analysed by the equivalent salt deposit density (ESDD) or non-soluble deposit density (NSDD) methods. In this study, a novel method called laser-induced breakdown spectroscopy (LIBS) offering the advantages of no sample preparation, being nearly nondestructive and having a fast speed was applied for the analysis of metal contamination. Several LIBS parameters (laser energy and delay time) were optimized to obtain better resolution of the spectral data. The limit of detection (LOD) of the observed elements was obtained using a calibration curve. Compared to calibration curves, multivariate analysis methods including principal component analysis (PCA), k-means and partial least squares regression (PLSR) showed their superiority in analyzing metal contamination in insulators. Then, the elemental distribution of natural pollution was predicted using LIBS to fully capture information about the bulk elements (Na, Ni, Cu, Mn, Ca, etc.) of entire areas with PLSR. The results showed that LIBS could be a promising method for accurate direct online quantification of metal contamination in insulators.

30 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023210
2022508
2021137
2020213
2019234
2018216