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Carboxylic acid
About: Carboxylic acid is a research topic. Over the lifetime, 48544 publications have been published within this topic receiving 605696 citations.
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TL;DR: In this article, Fourier transform infrared spectroscopy was used to identify five-membered cyclic an hydride intermediates formed under the curing conditions of polycarboxylic acids.
Abstract: Multifunctional polycarboxylic acids have been used as nonformaldehyde cross linking agents for cotton fabrics to replace the traditional N-methylol reagents. Ester ification of cotton cellulose by seventeen aliphatic and aromatic polycarboxylic acids is studied using Fourier transform infrared spectroscopy. Five-membered cyclic an hydride intermediates formed under the curing conditions are identified on cotton fabrics treated with these acids. Only those polycarboxylic acids that form cyclic an hydride intermediates esterify cotton cellulose. Formation of the cyclic anhydride intermediates and esterification of cotton cellulose take place in the same curing tem perature regions. The infrared spectroscopy data also indicate that the second carboxyl group in a bifunctional carboxylic acid is not able to esterify cotton cellulose effectively. Therefore, we can conclude that a polycarboxylic acid esterifies cotton cellulose through the formation of a cyclic anhydride intermediate. The infrared spectroscopy ...
181 citations
TL;DR: Two carboxylic acid derivatives of the herbicides atrazine and simazine were synthesized for use as haptens in the development of immunoassays.
Abstract: Two families of carboxylic acid derivatives of the herbicides atrazine and simazine were synthesized for use as haptens in the development of immunoassays. One family was made by using monosubstituted (alkylamino) cyanuric chlorides and a variety of ω-amino acids, giving spacers of varying lengths attached to one secondary amino group. The second family resulted from the replacement of the 2-chloro group of atrazine or simazine with 3-mercaptopropanoic acid (...)
180 citations
TL;DR: Using a previously reported chemical patterning approach, it is shown that DNA can be immobilized on silicon surfaces in spatially well-resolved domains.
Abstract: This paper describes a simple strategy for DNA immobilization on chemically modified and patterned silicon surfaces. The photochemical modification of hydrogen-terminated Si(111) with undecylenic acid leads to the formation of an organic monolayer covalently attached to the surface through Si-C bonds without detectable reaction of the carboxylic acid group, providing indirect support of a free radical mechanism. Chemical activation of the acid function was achieved by a simple chemical route using N-hydroxysuccinimide (NHS) in the presence of N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide hydrochloride. Single strand DNA with a 5'-dodecylamine group was then coupled to the NHS-activated surface by amide bond formation. Using a previously reported chemical patterning approach, we have shown that DNA can be immobilized on silicon surfaces in spatially well-resolved domains. Methoxytetraethyleneglycolamine was used to inhibit nonspecific adsorption. The resulting DNA-modified surfaces have shown good specificity and chemical and thermal stability under hybridization conditions. The sequential reactions on the surface were monitored by ATR-FTIR, X-ray Photoelectron Spectroscopy, and fluorescence spectroscopy.
180 citations
TL;DR: An asymmetric C(sp3 )-H amidation of thioamides using an achiral CoIII /chiral carboxylic acid hybrid catalytic system, which provides easy and straightforward access to chiral β-amino thiocarbonyl and β- amino carbonyl building blocks with a quaternary carbon stereocenter is described.
Abstract: Recent advances in Cpx MIII catalysis (M=Co, Rh, Ir) have enabled a variety of enantioselective C(sp2 )-H functionalization reactions, but enantioselective C(sp3 )-H functionalization is still largely unexplored. We describe an asymmetric C(sp3 )-H amidation of thioamides using an achiral CoIII /chiral carboxylic acid hybrid catalytic system, which provides easy and straightforward access to chiral β-amino thiocarbonyl and β-amino carbonyl building blocks with a quaternary carbon stereocenter.
180 citations
TL;DR: In this study, citric acid or acetic acid at higher concentrations had the greatest improvement of Pb(2+) desorption, followed by malic acid; and the smallest was oxalic acid.
180 citations