Topic
Catechu
About: Catechu is a research topic. Over the lifetime, 408 publications have been published within this topic receiving 4544 citations. The topic is also known as: cutch & black cutch.
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TL;DR: The methanol extracts of nine medicinal plants traditionally used in Chinese medicine screened for antioxidant activity versus resveratrol suggest that the plant extracts prevent oxidative damage in normal cells probably because of their antioxidant characteristics.
468 citations
TL;DR: One of them, arecatannin B1 showed significant HIV‐1‐PR inhibitory activity and was shown by the A. catechu extract, from which some procyanidins were isolated.
Abstract: To identify substances with anti-human immunodeficiency virus (HIV) activity in traditional medicines, water and methanol extracts of crude drugs used in Indian traditional medicine (Ayurveda) were subjected to screening for their inhibitory effects on HIV type 1 protease (PR) The enzyme activity was determined by HPLC and of the 39 crude drugs tested, the extracts of the seeds of Areca catechu, the bark of Eugenia jambolana, the bark of Saraca indica and the stem bark of Terminalia arjuna inhibited the HIV-1 PR activity by more than 70% at a concentration of 02 mg/mL The most potent inhibition was shown by the A catechu extract, from which some procyanidins were isolated One of them, arecatannin B1 showed significant HIV-1-PR inhibitory activity
191 citations
TL;DR: As an important herbal medicine, A. catechu has potential for the treatment of many diseases, especially parasitic diseases, digestive function disorders, and depression, and further research should be undertaken to investigate the clinical effects, toxic constituents, target organs, and pharmacokinetics.
178 citations
Journal Article•
TL;DR: Preparations from varieties of A. catechu nuts have been tested for their ability to stimulate collagen synthesis in microwell cultures of human fibroblasts, using a pulse of 3H-proline and subsequent analysis of the cultures for radioactive collagen.
158 citations
TL;DR: The data suggest a possible role of reactive oxygen species in the etiology of oral cancer in betel quid chewers.
129 citations