Topic
Cellular differentiation
About: Cellular differentiation is a research topic. Over the lifetime, 90966 publications have been published within this topic receiving 6099252 citations. The topic is also known as: Cellular differentiation & GO:0030154.
Papers published on a yearly basis
Papers
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TL;DR: XBP1 coordinates diverse changes in cellular structure and function resulting in the characteristic phenotype of professional secretory cells, and upregulates genes encoding many secretory pathway components.
965 citations
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TL;DR: Observations indicate that C/EBPalpha and beta remodel the transcription network of B cells into that of macrophages through a series of parallel and sequential changes that require endogenous PU.1.
964 citations
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TL;DR: Guided by the expression of Neurogenin 3 (Ngn3), the earliest islet cell-specific transcription factor in embryonic development, it is shown that beta cell progenitors can be activated in injured adult mouse pancreas and are located in the ductal lining.
964 citations
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TL;DR: The current understanding of the molecular and cellular basis of Hh morphogen gradient formation and signal transduction, and the multifaceted roles of HH signaling in development and tumorigenesis are reviewed.
963 citations
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TL;DR: It is proposed that multiple Breg cell subsets can be induced in response to inflammation at different stages in development, with a particular emphasis on their ontogeny.
961 citations