scispace - formally typeset
Search or ask a question
Topic

Chitin

About: Chitin is a research topic. Over the lifetime, 6590 publications have been published within this topic receiving 253993 citations.


Papers
More filters
Journal ArticleDOI
01 Jan 1990
TL;DR: It appears, this novel biomolecule, biodegradable, and biocompatible, find applications in substituting or regenerating the blood/tissue interfaces.
Abstract: Chitosan [a (1----4) 2-amino-2-deoxy-beta-D-Glucan] is a unique polysaccharide derived from chitin. Several attempts have been made to use this biopolymer in biomedical field. The use of this material in the development of hemodialysis membranes, artificial skin, drug targetting and other applications are discussed. It appears, this novel biomolecule, biodegradable, and biocompatible, find applications in substituting or regenerating the blood/tissue interfaces. This polysaccharide having structural characteristics similar to glycosaminoglycans, seems to mimic their functional behaviour.

728 citations

Journal ArticleDOI
TL;DR: Chitin is the world's second most abundant naturally occurring polysaccharide, and due to its widespread abundance, its chemical and physical versatility, and the problems of its disposal as a waste material, a wide range of value-added applications of chitin and chitosan are being initiated, investigated, and developed.
Abstract: Chitin is the world's second most abundant naturally occurring polysaccharide. Much of this is disposed of as waste from seafood crustacean, mainly in shrimps, prawns, crabs, and lobsters, where it occurs as a significant component in the shells/exoskeletons of crustacea. Due to its widespread abundance, its chemical and physical versatility, and the problems of its disposal as a waste material, a wide range of value-added applications of chitin and chitosan is being initiated, investigated, and developed. The widely ranging value-added applications of chitin and chitosan are presented in this review. Chitin and its derivative, chitosan, both highly stable and difficult to degrade materials, can be obtained as 10–20% w/w from the waste seafood shells by suitable chemical processing. One of the significant developments in the new range of applications is the study of the ability of chitosan, as a potentially major environmental treatment material, to remove metal ions from wastewaters. Chitosan is the deac...

694 citations

Journal ArticleDOI
TL;DR: As a nontoxic biodegradable material, as well as an elicitor, chitosan has the potential to become a new class of plant protectant, assisting towards the goal of sustainable agriculture.

687 citations

Journal ArticleDOI
01 Jun 2015
TL;DR: This study looks at the contemporary research in chitin and chitosan towards structure, properties, and applications in various industrial and biomedical fields.
Abstract: Chitin and chitosan are considerably versatile and promising biomaterials. The deacetylated chitin derivative chitosan is a useful and interesting bioactive polymer. Despite its biodegradability, it has many reactive amino side groups, which offer possibilities of chemical modifications, formation of a large variety of beneficial derivatives, which are commercially available or can be made available via graft reactions and ionic interactions. This study looks at the contemporary research in chitin and chitosan towards structure, properties, and applications in various industrial and biomedical fields.

670 citations

Journal ArticleDOI
TL;DR: Enzymatic procedures for deproteinization of the shells or mold mycelia and for chitin deacetylation were investigated and show that chit in is resistant to enzymatic de acetylation.
Abstract: Chitin is a polysaccharide composed from N-acetyl-D-glucosamine units. It is the second most abundant biopolymer on Earth and found mainly in invertebrates, insects, marine diatoms, algae, fungi, and yeasts. Recent investigations confirm the suitability of chitin and its derivatives in chemistry, biotechnology, medicine, veterinary, dentistry, agriculture, food processing, environmental protection, and textile production. The development of technologies based on the utilization of chitin derivatives is caused by their polyelectrolite properties, the presence of reactive functional groups, gel-forming ability, high adsorption capacity, biodegradability and bacteriostatic, and fungistatic and antitumour influence. Resources of chitin for industrial processing are crustacean shells and fungal mycelia. Fungi contain also chitosan, the product of N-deacetylation of chitin. Traditionally, chitin is isolated from crustacean shells by demineralization with diluted acid and deproteinization in a hot base solution. Furthermore, chitin is converted to chitosan by deacetylation in concentrated NaOH solution. It causes changes in molecular weight and a degree of deacetylation of the product and degradation of nutritionally valuable proteins. Thus, enzymatic procedures for deproteinization of the shells or mold mycelia and for chitin deacetylation were investigated. These studies show that chitin is resistant to enzymatic deacetylation. However, chitin deacetylated partially by chemical treatment can be processed further by deacetylase. Efficiency of enzymatic deproteinization depends on the source of crustacean offal and the process conditions. Mild enzymatic treatment removes about 90% of the protein and carotenoids from shrimp-processing waste, and the carotenoprotein produced is useful for feed supplementation. In contrast, deproteinization of shrimp shells by Alcalase led to the isolation of chitin containing about 4.5% of protein impurities and recovery of protein hydrolysate.

658 citations


Network Information
Related Topics (5)
Cellulose
59K papers, 1.4M citations
87% related
Enzyme
32.8K papers, 1.1M citations
81% related
Amino acid
124.9K papers, 4M citations
80% related
Fermentation
68.8K papers, 1.2M citations
80% related
Saccharomyces cerevisiae
32.1K papers, 1.6M citations
80% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023434
2022868
2021271
2020354
2019333
2018271