Topic
Chitosan
About: Chitosan is a research topic. Over the lifetime, 20011 publications have been published within this topic receiving 608714 citations. The topic is also known as: poliglusam.
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TL;DR: The current review of 129 references describes the biological activity of several chitosan derivatives and the modes of action that have been postulated in the literature.
2,615 citations
TL;DR: In this paper, a review discusses the various attempts reported on solving this problem from the point of view of the chemistry and the structure of these polymers highlighting the drawbacks and advantages of each method and proposes that based on considerations of structure-property relations, it is possible to obtain chitin fibers with improved strength by making use of their nanostructures and/or mesophase properties of chitins.
2,278 citations
TL;DR: Alginate, being an anionic polymer with carboxyl end groups, is a good mucoadhesive agent and cross-linked alginate has more capacity to retain the entrapped drugs and mixing of alginates with other polymers such as neutral gums, chitosan, and eudragit have been found to solve the problem of drug leaching.
1,724 citations
TL;DR: Application of chitinous products in foods and pharmaceuticals as well as processing aids has received considerable attention in recent years as exotic synthetic compounds are losing their appeal.
Abstract: Chitin is the second most abundant natural biopolymer after cellulose. The chemical structure of chitin is similar to that of cellulose with 2-acetamido-2-deoxy-β- d -glucose (NAG) monomers attached via β(14) linkages. Chitosan is the deacetylated (to varying degrees) form of chitin, which, unlike chitin, is soluble in acidic solutions. Application of chitinous products in foods and pharmaceuticals as well as processing aids has received considerable attention in recent years as exotic synthetic compounds are losing their appeal. This review summarizes some of the important developments related to food applications of chitin, chitosan and their derivatives.
1,711 citations
TL;DR: The preparation and properties of innovative chitosan-based biomaterials, with respect to their future applications, are highlighted, with a special focus on wound healing application.
1,694 citations