scispace - formally typeset
Search or ask a question
Topic

Citric acid

About: Citric acid is a research topic. Over the lifetime, 17745 publications have been published within this topic receiving 277125 citations. The topic is also known as: citrate & H3cit.


Papers
More filters
Journal ArticleDOI
TL;DR: In this paper, five sources of nitrogen, six minerals, six enzyme inducers and one each of growth as well as product promotors were screened by Plackett-Burman design, consisting of a total of 20 experiments for the above 19 sources/categories of medium ingredients, for their effect on the production of Aspergillus niger MRSS 234 in solid state fermentation system.
Abstract: Five sources of nitrogen, six minerals, six enzyme inducers and one each of growth as well as product promotors were screened by Plackett-Burman design, consisting of a total of 20 experiments for the above 19 sources/categories of medium ingredients, for their effect on the production of alpha-galactosidase by Aspergillus niger MRSS 234 in solid state fermentation system. The enzyme production was recorded from 2 to 5 days of fermentation. Data on enzyme titres was analysed by compatible analysis to obtain regression coefficients and t-ratios. Among the nitrogen sources, urea contributed positively to enzyme production and its effect increased with the fermentation time, in contrast to negative effect of all the ammonium salts used. Corn steep liquor, citric acid and legume seed flours showed significantly positive effects on enzyme production, though lactose showed negative effect upto 3 days of fermentation and then turned positive but not significantly. Calcium chloride and ferrous sulphate showed considerable negative effect, in contrast to mixed effect by other mineral salts studied. Among the legume seed flours, guar and French bean flours showed larger positive effects. The studies allowed the selection of urea, corn steep liquor, guar flour, soy bean flour and citric acid as most promising sources/categories for further optimization studies based on the effects as well as their trend with fermentation time. The use of Plackett-Burman design for rapid screening of large number of nutrients, in a very small number of experiments, for reliable short-listing of a few of most effective sources/categories for further optimization, has been scarce in submerged fermentation and never attempted earlier in solid state fermentation system.

101 citations

Journal ArticleDOI
TL;DR: It has been demonstrated that the production of citric acid from raw glycerol, in terms of specific production rate and conversion yield, was similar or even better as compared with that obtained during cultivation of yeasts or molds on various conventional media.
Abstract: Raw glycerol, produced in significant quantities during several industrial processes, could be further considered as a potential substrate for microbial conversions. In the present report, modelling approaches are used in order to quantify the kinetic behavior of microorganisms capable of producing growth- and non growth-associated metabolites when cultivated on raw glycerol. Citric acid production by Yarrowia lipolytica strain ACA-DC 50109 was successfully simulated by Monod-, Verhlust- and Williams-type models, while the optimized parameter values were found to be similar to those experimentally measured. It has been demonstrated that the production of citric acid from raw glycerol, in terms of specific production rate and conversion yield, was similar or even better as compared with that obtained during cultivation of yeasts or molds on various conventional (eg sugar-based) media. The production of 1,3-propanediol by Clostridium butyricum strain F2b from raw glycerol was successfully simulated by a Contois-type model. It was found that the maximum theoretical 1,3-propanediol productivity was comparable with the highest one achieved during growth of various bacterial strains on pure glycerol in batch and continuous cultures. Raw glycerol could be used as an alternative substrate for citric acid and 1,3-propanediol production, and possibly for other microbial products. Copyright © 2003 Society of Chemical Industry

101 citations

Journal ArticleDOI
03 May 2008
TL;DR: A possible microbial process for utilization of crude glycerol generated by the biodiesel industry for citric acid and erythritol production with an acetate negative mutant of Y. lipolytica Wratislavia K1 is shown.
Abstract: This study shows a possible microbial process for utilization of crude glycerol generated by the biodiesel industry for citric acid and erythritol production. Simultaneous production of citric acid and erythritol under nitrogen-limited conditions with glycerol as the carbon source was achieved with an acetate negative mutant of Y. lipolytica Wratislavia K1 in fed-batch cultivations. The effect of the initial glycerol concentration (from 30–180 g dm−3) on the citrate and erythritol production was investigated. As a result of the experiments, maximum citric acid production (110 g dm−3) and a very high amount of erythritol (81 g dm−3) were determined after 168 h of fed-batch cultivation with the initial glycerol concentration of 150 g dm−3 and the total glycerol concentration of 250 g dm−3. In addition, the citric acid to isocitric acid ratio of the products from this strain was 35.5:1.

100 citations

Journal ArticleDOI
TL;DR: Significant differences were observed in microhardness among the test groups, citric acid group being the least hard (p 0.05).

100 citations

Journal ArticleDOI
TL;DR: The production of citric and gluconic acids from fig by Aspergillus niger ATCC 10577 in solid-state fermentation was investigated and the addition of 6% (w/w) methanol into substrate increased the concentration from 64 and 490 to 96 and 685 g/kg dry fig, respectively.
Abstract: The production of citric and gluconic acids from fig by Aspergillus niger ATCC 10577 in solid-state fermentation was investigated. The maximal citric and gluconic acids concentration (64 and 490 g/kg dry figs, respectively), citric acid yield (8%), and gluconic acid yield (63%) were obtained at a moisture level of 75%, initial pH 7.0, temperature 30°C, and fermentation time in 15 days. However, the highest biomass dry weight (40 g/kg wet substrate) and sugar utilization (90%) were obtained in cultures grown at 35°C. The addition of 6% (w/w) methanol into substrate increased the concentration of citric and gluconic acid from 64 and 490 to 96 and 685 g/kg dry fig, respectively. Journal of Industrial Microbiology & Biotechnology (2000) 25, 298–304.

100 citations


Network Information
Related Topics (5)
Ascorbic acid
93.5K papers, 2.5M citations
84% related
Antioxidant
37.9K papers, 1.7M citations
83% related
Aqueous solution
189.5K papers, 3.4M citations
82% related
Calcium
78.5K papers, 2.2M citations
82% related
Fatty acid
74.5K papers, 2.2M citations
81% related
Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023725
20221,540
2021441
2020597
2019678
2018823