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Coturnix
About: Coturnix is a research topic. Over the lifetime, 953 publications have been published within this topic receiving 23305 citations.
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TL;DR: It is demonstrated that DEHP-induced nephrotoxicity in quail was associated with activating Nrf2-mediated antioxidant defense response and UPR signaling pathway.
62 citations
TL;DR: A quail cDNA clone is isolated, named QR1, encoding a 676-amino acid protein whose carboxyl-terminal portion shows significant similarity to those of the extracellular glycoprotein osteonectin/SPARC/BM40 and of the recently described SC1 protein.
Abstract: The avian neuroretina (NR) is part of the central nervous system and is composed of photoreceptors, neuronal cells, and Muller (glial) cells. These cells are derived from proliferating neuroectodermal precursors that differentiate after terminal mitosis and become organized in cell strata. Genes that are specifically expressed at the various stages of retinal development are presently unknown. We have isolated a quail (Coturnix coturnix japonica) cDNA clone, named QR1, encoding a 676-amino acid protein whose carboxyl-terminal portion shows significant similarity to those of the extracellular glycoprotein osteonectin/SPARC/BM40 and of the recently described SC1 protein. The QR1 cDNA identifies a mRNA detected in NR but not in other embryonic tissues examined. The levels of this mRNA are markedly reduced when nondividing NR cells are induced to proliferate by the v-src oncogene. QR1 expression in NR is limited to the middle portion of the inner nuclear layer, a localization that essentially corresponds to that of Muller cells. Transcription of QR1 takes place only during the late phase of retinal development and is shut off sharply at hatching. Signals that regulate this unique pattern of expression appear to originate within the NR, since the QR1 mRNA is transcribed in cultured NR cells and is shut off also in vitro at a time coinciding with hatching.
62 citations
TL;DR: Findings on the effect of various photoperiods on the sexual development and reproductive performance of Coturnix are presented.
62 citations
TL;DR: A summary of reproductive development and sexual differentiation in intact Japanese quail embryos is provided, including ontogenetic patterns in steroid hormones in the embryonic and maturing quail.
62 citations
TL;DR: This study reports direct evidence for additive genetic variance of maternal androgens through a bidirectional selection on yolk testosterone levels in Japanese quail, seriously challenging the hypothesis that transfer of maternal hormones to offspring is constrained by hormone levels in a mother’s circulation.
Abstract: In many animal species, embryos are exposed to maternal hormones that affect their development. Maternal hormone transfer varies with environmental conditions of the mother and is often interpreted as being shaped by natural selection to adjust the offspring to prevailing environmental conditions. Such hormone transfer requires genetic variability, which has not yet been experimentally demonstrated. Our study reports direct evidence for additive genetic variance of maternal androgens through a bidirectional selection on yolk testosterone (T) levels in Japanese quail. Lines selected for high egg T (HET) and low egg T (LET) concentration differed in yolk levels of this androgen, resulting in high realized heritability (). Correlated responses to selection on other gonadal hormones indicated that selection specifically targeted biologically active androgens. Eggs of HET quail contained higher androstenedione and lower estradiol concentrations than did those of LET quail, with no line differences in y...
62 citations