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Coturnix

About: Coturnix is a research topic. Over the lifetime, 953 publications have been published within this topic receiving 23305 citations.


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TL;DR: In the eight-week-old quail, no significant differences were noted between irradiated and control cerebella in the morphological measurements of Purkinje cells, and the long-term effect of microwave radiation during embryogenesis on the cerebellum was examined.
Abstract: Fertilized Japanese quail eggs were continuously exposed to 2.45 GHz microwave radiation from day 1 through day 12 of incubation at a power density of 5.0 +/- 0.52 mW/cm2 (mean specific absorption rate = 4.03 mW/gm). In the experiment with embryos, irradiated and control embryos were removed from eggs on day 12, 13 or 14 of incubation and the cerebella were histologically examined. In order to examine the long-term effect of microwave radiation during embryogenesis on the cerebellum, some of the quail were allowed to hatch and were reared to eight weeks of age. Their cerebella were histologically examined, and the extent of dendritic arbores, the length of the stem of the primary dendrite, and the size of the perikaryon of Purkinje cells were measured in Golgi-Cox impregnated sections. In the irradiated embryos, a slight developmental retardation was found in the cerebellar cortices in terms of several morphological parameters. The effects included the growth and subsequent decline of the external granular layer, the growth of the molecular layer, the cellular differentiation and the alignment of Purkinje cells, and the accumulation of granule cells beneath the Purkinje cell layer, as well as lower body and brain weights. In the eight-week-old quail, no significant differences were noted between irradiated and control cerebella in the morphological measurements of Purkinje cells.

18 citations

Journal ArticleDOI
TL;DR: Results with chick hepatocytes and quail, showing uroporphyrin accumulation without a decrease in uropoiryrinogen decarboxylase activity, are consistent with a new two-stage model of the uroporphyria.
Abstract: The relationship between hepatic uroporphyrin accumulation and uroporphyrinogen decarboxylase (EC 4.1.1.37) activity was investigated in cultured chick-embryo hepatocytes, Japanese quail (Coturnix coturnix japonica) and mice that had been treated with polyhalogenated aromatic compounds. Chick-embryo hepatocytes treated with 3,3',4,4'-tetrachlorobiphenyl accumulated uroporphyrin in a dose-dependent fashion without a detectable decrease in uroporphyrinogen decarboxylase activity when either pentacarboxyporphyrinogen III or uroporphyrinogen III were used as substrates in the assay. Other compounds, such as hexachlorobenzene, parathion, carbamazepine and nifedipine, which have been shown previously to cause uroporphyrin accumulation in these cells, did not decrease uroporphyrinogen decarboxylase activity. Japanese quail treated with hexachlorobenzene for 7-10 days also accumulated hepatic uroporphyrin without any decrease in uroporphyrinogen decarboxylase activity. In contrast, hepatic uroporphyrin accumulation in male C57BL/6 mice treated with iron and hexachlorobenzene was accompanied by a 20-80% decrease in uroporphyrinogen decarboxylase activity, demonstrating that the assay used for uroporphyrinogen decarboxylase, using pentacarboxyporphyrinogen III as substrate, could detect decreased enzyme activity. Our results with chick hepatocytes and quail, showing uroporphyrin accumulation without a decrease in uroporphyrinogen decarboxylase activity, are consistent with a new two-stage model of the uroporphyria: initially uroporphyrinogen is oxidized by a cytochrome P-450-mediated reaction, followed in rodents by a progressive decrease in uroporphyrinogen decarboxylase activity.

18 citations

Journal ArticleDOI
TL;DR: Results indicated that a part of MDV genome or another related herpes virus genome was integrated into the host DNA of SUS quail, believed to be important in atherogenesis, because they are genetically co-selected with the atherosclerosis-susceptibility.

18 citations

Journal ArticleDOI
TL;DR: In Japanese quail, SRC-2 expression was found to be nearly ubiquitous with high levels of expression in kidney, cerebellum and diencephalon, and real-time quantitative PCR did not reveal any differences between intact males and females the medial preoptic nucleus (POM), optic lobes and cerebellal as discussed by the authors.
Abstract: J. Neurochem. (2011) 119, 579–593. Abstract Steroid receptor coactivators are necessary for efficient transcriptional regulation by ligand-bound nuclear receptors, including estrogen and androgen receptors. Steroid receptor coactivator-2 (SRC-2) modulates estrogen- and progesterone-dependent sexual behavior in female rats but its implication in the control of male sexual behavior has not been studied to our knowledge. We cloned and sequenced the complete quail SRC-2 transcript and showed by semi-quantitative PCR that SRC-2 expression is nearly ubiquitous, with high levels of expression in the kidney, cerebellum and diencephalon. Real-time quantitative PCR did not reveal any differences between intact males and females the medial preoptic nucleus (POM), optic lobes and cerebellum. We next investigated the physiological and behavioral role of this coactivator using in vivo antisense oligonucleotide techniques. Daily injections in the third ventricle at the level of the POM of locked nucleic acid antisense targeting SRC-2 significantly reduced the expression of testosterone-dependent male-typical copulatory behavior but no inhibition of one aspect of the appetitive sexual behavior was observed. The volume of POM, defined by aromatase-immunoreactive cells, was markedly decreased in animals treated with antisense as compared with controls. These results demonstrate that SRC-2 plays a prominent role in the control of steroid-dependent male sexual behavior and its associated neuroplasticity in Japanese quail.

18 citations

Journal ArticleDOI
TL;DR: Folacin deficiency in growing Japanese quail caused poor feathering, high mortality, leg weakness and cervical paralysis, and a curly-toe system was observed in coturnix chicks fed low levels of folacin and might also be a consequence of folACin deficiency.

18 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
202312
202232
20211
202011
20197
201813