Showing papers on "Cuneate nucleus published in 1974"
TL;DR: The successive degeneration technique was used to demonstrate the existence of non-primary afferents to the cuneate nucleus in the dorsal funiculus of the brachial cord of cat and provides a basis for the re-interpretation of several functional aspects concerning integration of impulses through the dorsal column nuclei.
101 citations
TL;DR: K+-selective microelectrodes were used to measure extracellular K+ activity in the neuraxis of cats under Dial and found that there is a cumulative, maintained rise in aK during repetitive stimulation at rates > 0.5 s−1, and definite changes can be recorded even with single pulses.
Abstract: K+-selective microelectrodes were used to measure extracellular K+ activity (aK) in the neuraxis of cats under Dial. In resting conditions, aK is stable (in range 2.0–3.0 mM) but may vary systemati...
64 citations
TL;DR: The present findings support the suggestion of Cooper and Sherrington pointing to the existence of spinocerebellar fibers originating in the border cells of the ventral horn at the level of the low thoracic and lumbar segments of the cord.
41 citations
TL;DR: The inhibition is accompanied by an increase in the amplitude of the antidromic wave recorded in the superficial radial nerve, thus indicating that the inhibitory effects caused by vago-aortic nerve stimulation seem to be of a presynaptic origin.
36 citations
TL;DR: The corticocuneate pathway appeared to provide a negative feedback circuit which may be used to modulate transmission of sensory input in cortex during seizure and during cortical epileptiform activity.
32 citations
TL;DR: Folic acid applied topically in solution to the rat cuneate nucleus reduced presynaptic inhibition produced by peripheral stimulation, and this resembles the action of picrotoxin in the same animals and it is possible that these two convulsants are acting in a similar manner by blockade of the receptors for thePresynaptic inhibitory transmitter.
Abstract: Folic acid applied topically in solution to the rat cuneate nucleus reduced presynaptic inhibition produced by peripheral stimulation. This resembles the action of picrotoxin in the same animals and it is possible that these two convulsants are acting in a similar manner by blockade of the receptors for the presynaptic inhibitory transmitter.
21 citations
TL;DR: The effects of light flashes or sound clicks on somatic sensory activity in the cuneate nucleus of the cat were studied and polysensory interactions were demonstrated by means of gross potential recording in the beryllium or medial lemniscus, and excitability testing of tract terminals.
Abstract: 1. The effects of light flashes or sound clicks on somatic sensory activity in the cuneate nucleus of the cat were studied. Polysensory interactions were demonstrated by means of gross potential recording in the cuneate nucleus or medial lemniscus, single unit recording in the cuneate nucleus, and excitability testing of tract terminals.2. Brief flashes or clicks were found to produce negative (N) and positive (P) waves in the cuneate nucleus similar to those produced by cutaneous stimulation. Furthermore, the P wave evoked by conditioning photic or acoustic stimuli depressed the P wave produced by cutaneous test stimuli.3. Conditioning photic or acoustic stimuli inhibited spontaneously firing cuneate neurones as well as those driven by cutaneous test stimuli.4. Conditioning photic or acoustic stimuli depressed the test discharge in the medial lemniscus evoked by cutaneous test stimuli.5. Micro-electrode stimulation within the cuneate nucleus evoked an antidromic response in the superficial radial nerve consisting of two spike complexes. Conditioning photic or acoustic stimuli caused an increase in the size of the initial spike complex and a depression in the secondary spike complex. These changes and the time courses of all the interactions observed were suggestive of presynaptic inhibition.6. The modulatory influences of photic and acoustic stimuli on the cuneate nucleus were present under alpha-chloralose or pentobarbitone anaesthesia and the acoustic influence persisted after midcollicular decerebration. When added to other evidence, the above findings suggest that the reticular formation of the brain stem plays an important role in these polysensory interactions.
11 citations
TL;DR: The influence of corticofugal discharges on transmission of sensory information through the cuneate nucleus was determined to be inhibitory, for nerve-evoked field potentials in the cunate output pathway (medial lemniscus) were depressed during cortical epileptiform events.
10 citations
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2 citations