Topic
Deep transcranial magnetic stimulation
About: Deep transcranial magnetic stimulation is a research topic. Over the lifetime, 1127 publications have been published within this topic receiving 38210 citations.
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TL;DR: The present updated guidelines review issues of risk and safety of conventional TMS protocols, address the undesired effects and risks of emerging TMS interventions, the applications of TMS in patients with implanted electrodes in the central nervous system, and safety aspects of T MS in neuroimaging environments.
4,447 citations
TL;DR: The guidelines for the use of rTMS cover the ethical issues, recommended limits on stimulation parameters, monitoring of subjects (both physiologically and neuropsychologically), expertise and function of the rT MS team, medical and psychosocial management of induced seizures, and contra-indications to r TMS.
2,313 citations
TL;DR: Transcranial magnetic stimulation was effective in treating major depression with minimal side effects reported and offers clinicians a novel alternative for the treatment of this disorder.
1,426 citations
TL;DR: The clinical and scientific bases for using repetitive TMS (rTMS) as treatment are discussed, the results of trials in psychiatric and neurological disorders to date are reviewed, andResults of blinded, sham-controlled trials are reviewed.
577 citations
TL;DR: These placebo-controlled results suggest that daily left prefrontal repetitive transcranial magnetic stimulation has antidepressant activity when administered at these parameters.
Abstract: Objective: Preliminary studies have indicated that daily left prefrontal repetitive transcranial magnetic stimulation might have antidepressant activity. The authors sought to confirm this finding by using a double-blind crossover design. Method: Twelve depressed adults received in random order 2 weeks of active treatment (repetitive transcranial magnetic stimulation, 20 Hz at 80% motor threshold) and 2 weeks of sham treatment. Results: Changes from the relevant phase baseline in scores on the 21-item Hamilton depression scale showed that repetitive transcranial magnetic stimulation significantly improved mood over sham treatment. During the active-treatment phase, Hamilton depression scale scores decreased 5 points, while during sham treatment the scores increased or worsened by 3 points. No adverse effects were noted. Conclusions: These placebo-controlled results suggest that daily left prefrontal repetitive transcranial magnetic stimulation has antidepressant activity when administered at these parameters. Further controlled studies are indicated to explore optimal stimulation characteristics and location, potential clinical applications, and possible mechanisms of action. (Am J Psychiatry 1997; 154:1752‐1756)
524 citations