Topic
Depression (differential diagnoses)
About: Depression (differential diagnoses) is a research topic. Over the lifetime, 56557 publications have been published within this topic receiving 2048357 citations.
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TL;DR: The findings suggest that the prevalence of depression and anxiety in men with prostate cancer, across the treatment spectrum, is relatively high and further research is warranted to ensure that psychological distress in patients with prostatecancer is not underdiagnosed and undertreated.
Abstract: Objectives: To systematically review the literature pertaining to the prevalence of depression and anxiety in patients with prostate cancer as a function of treatment stage. Design: Systematic review and meta-analysis. Participants: 4494 patients with prostate cancer from primary research investigations. Primary outcome measure: The prevalence of clinical depression and anxiety in patients with prostate cancer as a function of treatment stage. Results: We identified 27 full journal articles that met the inclusion criteria for entry into the meta-analysis resulting in a pooled sample size of 4494 patients. The meta-analysis of prevalence rates identified pretreatment, on-treatment and post-treatment depression prevalences of 17.27% (95% CI 15.06% to 19.72%), 14.70% (95% CI 11.92% to 17.99%) and 18.44% (95% CI 15.18% to 22.22%), respectively. Pretreatment, on-treatment and post-treatment anxiety prevalences were 27.04% (95% CI 24.26% to 30.01%), 15.09% (95% CI 12.15% to 18.60%) and 18.49% (95% CI 13.81% to 24.31%), respectively. Conclusions: Our findings suggest that the prevalence of depression and anxiety in men with prostate cancer, across the treatment spectrum, is relatively high. In light of the growing emphasis placed on cancer survivorship, we consider that further research within this area is warranted to ensure that psychological distress in patients with prostate cancer is not underdiagnosed and undertreated.
350 citations
TL;DR: Depression occurred as frequently during late pregnancy and after delivery as in developed countries, but there were cultural differences in risk factors.
Abstract: Background Community-based epidemiological data on post-partum depression from developing countries are scarce.
Aims To determine the incidence of and risk factors for developing post-partum depression in a cohort of women living in rural south India.
Method We assessed 359 women in the last trimester of pregnancy and 6-12 weeks after delivery for depression and for putative risk factors.
Results The incidence of post-partum depression was 11% (95% CI 7.1-14.9). Low income, birth of a daughter when a son was desired, relationship difficulties with mother-in-law and parents, adverse life events during pregnancy and lack of physical help were risk factors for the onset of post-partum depression.
Conclusions Depression occurred as frequently during late pregnancy and after delivery as in developed countries, but there were cultural differences in risk factors. These findings have implications for policies regarding maternal and childcare programmes.
349 citations
TL;DR: Evidence on the benefits and harms of screening primary care patients for depression, including direct evidence that depression screening programs improve health outcomes, is examined.
Abstract: Description Update of the 2002 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for depression in adults. Methods The USPSTF examined evidence on the benefits and harms of screening primary care patients for depression, including direct evidence that depression screening programs improve health outcomes. The USPSTF did not reexamine evidence for those key questions that had strong, consistent evidence in the 2002 review, including questions about the accuracy of screening instruments in identifying depressed adult patients in primary care settings, and the efficacy of treatment of depressed adults with antidepressants or psychotherapy. New areas of evidence considered for this review (and not reviewed in 2002) include efficacy of treatment of depression in older adult patients, harms of screening for depression in primary care settings, and adverse events from treatment of depression in adults. Recommendations The USPSTF recommends screening adults for depression when staff-assisted depression care supports are in place to assure accurate diagnosis, effective treatment, and follow-up. (Grade B recommendation) The USPSTF recommends against routinely screening adults for depression when staff-assisted depression care supports are not in place. There may be considerations that support screening for depression in an individual patient. (Grade C recommendation).
349 citations
TL;DR: The findings indicate that adolescents exposed to multiple traumas are more likely to experience more severe symptoms of PTSD and depression than those who experience a single event, with this effect independent of childhood adversity and everyday stressful life experiences.
349 citations