Topic
Depression (differential diagnoses)
About: Depression (differential diagnoses) is a research topic. Over the lifetime, 56557 publications have been published within this topic receiving 2048357 citations.
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TL;DR: No evidence is available on symptom prevalence in ESRD patients managed conservatively (without dialysis), but evidence in patients discontinuing dialysis suggests they too have significant symptom burden.
781 citations
TL;DR: A modest relationship between self-reported symptoms of depression and the diagnosis of a major or minor depression is indicated and symptom scales are only rough indicators of clinical depression in the community.
Abstract: The authors gave the CES-D, a self-report depression symptom scale, to 515 people drawn from a longitudinal community survey. The subjects were also interviewed using the Schedule for Affective Disorders and Schizophrenia (SADS). From the information collected on the SADS, the subjects were given diagnoses based on Research Diagnostic Criteria. The results indicate a modest relationship between self-reported symptoms of depression and the diagnosis of a major or minor depression. However, the groups defined as "cases" by such reports also include many people with other diagnoses or with no diagnoses at all. Thus, symptom scales are useful for the screening of depressed persons in research studies but are only rough indicators of clinical depression in the community.
779 citations
TL;DR: Residual symptoms were more common in subjects with more severe initial illness, but were not related to any other predictors, including longer prior illness, dysthymia, or lower dose of drug treatment during the illness episode.
Abstract: This paper draws attention to an important adverse outcome in depression, the occurrence of residual symptoms after partial remission. Among patients with definite major depression followed every 3 months to remission and thereafter, residual symptoms reaching 8 or more on the Hamilton Depression Scale 17-item total were present in 32% (19) of the 60 who remitted below major depression by 15 months. The pattern was of mild but typical depressive symptoms. Residual symptoms were more common in subjects with more severe initial illness, but were not related to any other predictors, including longer prior illness, dysthymia, or lower dose of drug treatment during the illness episode. There were weak associations with personality that might have been consequences of symptom presence. Residual symptoms were very strong predictors of subsequent early relapse, which occurred in 76% (13/17) of those with residual symptoms and 25% (10/40) of those without.
779 citations
TL;DR: Despite substantial differences between characteristics of people who commit suicide in China and the west, risk factors for suicide do not differ greatly and prevention programmes that concentrate on a single risk factor are unlikely to reduce suicide rates substantially.
778 citations
TL;DR: Evidence of a bidirectional relationship between cancer and depression, offering new opportunities for therapeutic intervention is found, although studies in this latter area are also divided.
778 citations