Showing papers on "Derivative (chemistry) published in 1968"
219 citations
173 citations
TL;DR: In this paper, 3-Amino-3-deoxy-D-ribose and Dribose were prepared from a derivative of D-xylose, which yielded D-riboses on hydrolysis.
Abstract: 3-Amino-3-deoxy-D-ribose and D-ribose were prepared from a derivative of D-xylose. 1,2-O-Isopropylidene-5-O-triphenylmethyl-α-D-xylofuranose (2) was oxidized by dimethyl sulfoxide – acetic anhydride to 1,2-O-isopropylidene-5-O-triphenylmethyl-α-D-erythro-pentofuranos-3-ulose (3). The oxime (4) of this 3-keto sugar derivative was reduced with lithium aluminium hydride to 3-amino-3-deoxy-1,2-O-isopropylidene-5-O-triphenylmethyl-α-D-ribofuranose (5), isolated as the acetamido derivative (6). Hydrolysis yielded 3-amino-3-deoxy-D-ribose hydrochloride. 3 was reduced by sodium borohydride to 1,2-O-isopropylidene-5-O-triphenylmethyl-α-D-ribofuranose (7), which yielded D-ribose on hydrolysis.
52 citations
51 citations
45 citations
TL;DR: 2-Methyl-2-[p-(1,2,3,4-4-tetrahydro-1-naphthyl)-phenoxy]-propion-säure (CIBA 13,437-Su)stellt ein oral aktives Tetralin-Derivat dar, welches ausgeprägte Blutlipid-senkende Eigenschaften besitzt.
Abstract: 2-Methyl-2-[p-(1,2,3,4-tetrahydro-1-naphthyl)-phenoxy]-propion-saure (CIBA 13,437-Su)stellt ein oral aktives Tetralin-Derivat dar, welches ausgepragte Blutlipid-senkende Eigenschaften besitzt. Die hypolipidaemische Wirkung wurde bei mehreren Spezies untersucht und umfasste sowohl Cholesterin wie Glyzeride.
42 citations
TL;DR: In this article, the limitations of the octant rule are discussed on the basis of existin theories, and the vicinal effects of some β-substituted adamantane-diones are found to be relatively small.
41 citations
41 citations
TL;DR: Arginine has been converted into a suitable pyrimidine derivative to permit its qualitative analysis in the presence of other amino acids by means of mass spectrometric and gas-chromatographic techniques as discussed by the authors.
Abstract: Arginine has been converted into a suitable pyrimidine derivative to permit its qualitative analysis in the presence of other amino acids by means of mass spectrometric and gas-chromatographic techniques.
35 citations
35 citations
TL;DR: In this article, it was proposed that these salts result from an intramolecular reaction of initially formed alkylation products, in which case the initial alkyl product undergoes an intramerolecular condensation with subsequent hydrogen chloride elimination.
TL;DR: According to the results mostly deduced from nuclear magnetic resonance and mass spectral analyses, licoricidin would be represented as being 3', 6-diisopentenyl-2', 4', 5-trihydroxy-7-methoxyisoflavan (IXa).
Abstract: A new isoflavan derivative, licoricidin, C25H32O5, mp 161-162.5°, [α]22.5°D+20° (MeOH) was isolated from licorice root. According to the results mostly deduced from nuclear magnetic resonance and mass spectral analyses, licoricidin would be represented as being 3', 6-diisopentenyl-2', 4', 5-trihydroxy-7-methoxyisoflavan (IXa).
TL;DR: In this paper, an improved 1,3,5-trisubstituted benzenes with the following substituents were described: CH 2Cl, CH 2OEt, CH2OBz, and [CH 2]2X (X = OH, OAc, OCBz, Cl, Br, CN, or CO2H).
Abstract: Syntheses are described of 1,3,5-trisubstituted benzenes with the following substituents CH2Cl, CH2OEt, CH2OBz, and [CH2]2X (X = OH, OAc, OCBz, Cl, Br, CN, or CO2H), an improved route to 1,3,5-tris(hydroxymethyl)-benzene and alternative routes to the corresponding tri-aldehyde and tris(bromomethyl) derivative.
Patent•
16 Feb 1968
Patent•
12 Jul 1968
TL;DR: In this paper, a method for suppressing the nitrification of ammonium nitrogen in soil comprising treating the soil in a plant growing area with a sulfanilamide derivative and a composition therefore.
Abstract: A method for suppressing the nitrification of ammonium nitrogen in soil comprising treating the soil in a plant growing area with a sulfanilamide derivative and a composition therefore.
Patent•
09 May 1968TL;DR: In this paper, the process for extraction and purification of phosphoric acid from impure solutions of acid attack of phosphate rock is described, where the impure solution is first passed in countercurrent flow with an alkyl derivative of the acid acid for removal of the removed acid from the impured solution.
Abstract: The process for extraction and purification of phosphoric acid from impure solutions of phosphoric acid derived by acid attack of phosphate rock wherein the impure solution is first passed in countercurrent flow with an alkyl derivative of phosphoric acid for removal of phosphoric acid from the impure solution and then passing the alkyl phosphoric acid derivative containing the removed phosphoric acid in countercurrent flow with an aqueous medium whereby the latter removes purified phosphoric acid from the solution.
TL;DR: The chlorinated monoanthrone derivative is the first case in natural products.
Abstract: Several new pigments produced by a fungus A spergillus fumigatus (J-4) were studied. The structures were determined as 2-chloro-1, 3, 8-trihydroxy-6-methylanthrone (9) (I), 2-chloro-1, 3, 8-trihydroxy-6-methylanthraquinone (II), 2-chloro-1, 3, 8-trihydroxy-6-hydroxymethylanthraquinone (III) and emodin. The chlorinated monoanthrone derivative is the first case in natural products. When Cl- was replaced by Br-in the medium, the fungus produced corresponding brominated anthrone (IV).
TL;DR: The structure of 1,3- or 1,5-Cyclo-Octadiene has been confirmed by single-crystal X-ray analysis in this article, based on infrared, proton magnetic resonance, and mass spectra.
Abstract: 1,3- or 1,5-Cyclo-octadiene undergoes transannular dehydrogenation with decacarbonyldirhenium to give the bicyclic derivative, tricarbonyltrimethylene-1,2-cyclopentadienylrhenium(I), C8H9Re(CO)3. The structure of the product, suggested on the basis of infrared, proton magnetic resonance, and mass spectra, has been confirmed by single-crystal X-ray analysis. The Re(CO)3 group is bonded to the cyclopentadienyl ring in the same way as in many [M(CO)3Arene] complexes.
TL;DR: In this article, the preparation of 5-methyl-3-phenylisothiazole-4-carboxylic acid (Xa) and related compounds are described.
Abstract: Preparations of 5-methyl-3-phenylisothiazole-4-carboxylic acid (Xa) and related compounds are described. 3-(Halogen-substituted phenyl)-5-methylisothiazole-4-carboxylic acids were also obtained by halogenation of 4-cyano-5-methyl-3-phenylisothiazole (VIIa), followed by hydrolysis. 5-Bromo-3-phenylisothiazole-4-carboxylic acid (XV) was prepared, and converted into the 5-methylthio derivative (XVI) which was oxidized to the corresponding sulfoxide (XVII) and sulfone (XVIII).
TL;DR: In this article, the optical spectra of transition and noble metals are reviewed and interpreted from the viewpoint of energy-band theory, and photo-emission studies of the spectra are presented.
Abstract: Derivative and photoemission studies of the optical spectra of transition and noble metals are reviewed and interpreted from the viewpoint of energy‐band theory.