Showing papers on "Derivative (chemistry) published in 1986"
TL;DR: In this article, a novel Ti derivative of Silicalite-1 has been prepared by hydrothermal procedure with (n-C 3 H 7 )N-OH, and X-ray, IR, EDX, and 29 Si MAS NMR investigations indicate an homogeneous distribution of Ti in the crystal while suggesting replacement of Ti for Si in the framework.
Abstract: A novel Ti derivative of Silicalite-1 has been prepared by hydrothermal procedure with (n-C 3 H 7 )N-OH. X-ray, IR, EDX, and 29 Si MAS NMR investigations indicate an homogeneous distribution of Ti in the crystal while suggesting replacement of Ti for Si in the framework. TS-1 catalyzes reactions involving H 2 O 2 such as the direct hydroxylation of aromatics with high selectivity towards para isomers. Moreover, it selectively epoxidizes olefins and oxidizes alcohols to aldehydes or ketones, with high yield. Due to the pore structure of TS-1, minimization of useless byproducts is obtained in reactions involving aromatic hydrocarbons.
269 citations
Patent•
10 Jan 1986
TL;DR: In this paper, the same surface-modifier was used to promote electron transfer to either a positively or a negatively charged protein using a compound of formula 4,4'-bipyridyl or a derivative thereof.
Abstract: In a bioelechemical process in which the electrons are transferred directly, without use of a mediator, such as a redox dye or cofactor, between an electrode and an electroactive biological material, such as an enzyme or a protein, in either direction, rapid electron transfer has previously been achieved between an electrode and the positively charged protein horse-heart cytochrome c by adding a surface-modifier such as 4,4'-bipyridyl or a derivative thereof. It has now been found possible to promote electron transfer to either a positively or a negatively charged protein using the same surface-modifier for either job, namely a compound of formula
wherein: The puridine ring shown in substituted in the 2-,
3- or 4-position by the (methylene)hydrazinecar- bothioamide group shown; R' represents hydrogen atom(s) or one or two methyl or ethyl groups in the 2-, 3- or 4-position (when the said position is not substituted by the (methylene)hydrazinecar- bothioamide group shown); R 2 represents a hydrogen atom or a methyl group; R 3 represents a hydrogen atom or a methyl group; and R 4 represents a hydrogen atom or a methyl group.
103 citations
TL;DR: In this article, a non-metalated chlorophyll derivative has been isolated from Darwinella oxeata (Bergquist) and its structure determined by physical and X-ray measurements.
75 citations
Patent•
10 Dec 1986TL;DR: An external medicament comprises a novel amide derivative represented by the following formula (I) as mentioned in this paper, which provides excellent improving and preventing effects for chapping of the skin, and is applicable to both a pharmaceutical external medicine and a cosmetic composition.
Abstract: An external medicament comprises a novel amide derivative represented by the following formula (I). ##STR1## The external medicament is applicable to both a pharmaceutical external medicament and a cosmetic composition, and it provides excellent improving and preventing effects for chapping of the skin.
73 citations
TL;DR: The ability of aryl and alkyl isothiocyanates to react with reducing agents such as triethyl phosphite, triethylphosphine, or triphenyltin hydride to form the corresponding isocyanide is elaborated in the chapter.
Abstract: Publisher Summary This chapter presents the synthesis, chemistry, and preparative applications of monosaccharide isothiocyanates and thiocyanates. The ability of the isothiocyanate group to participate in nucleophilic reaction provides an attractive approach to nucleoside analogs and other nitrogen and sulfur heterocycles. Sugar thiocyanates are generally good precursors for the synthesis of thio and deoxy sugars and they are readily synthesized by a variety of methods from the corresponding halides. The thermodynamically more-stable isothiocyanate may also be formed by a secondary, isomerization reaction. It is found that that the treatment of semicarbazide with a nitroso acid at 0° affords the 1,2,3,4-thiatriazole derivative by addition and cyclization. The same 1,2,3,4-thiatriazole derivative 39 was obtained by the treatment of isothiocyanate 2 with hydrazoic acid. It is observed that isothiocyanate reacts with glycine, as well as with β-alanine, in tetrahydrofuran (THF) solution with the formation of corresponding N -(carboxyalky1)- d -gluconamides by nucleophilic attack of the amino group on the hard site, with simultaneous elimination of a molecule of thiocyanogen. The ability of aryl and alkyl isothiocyanates to react with reducing agents such as triethyl phosphite, triethylphosphine, or triphenyltin hydride to form the corresponding isocyanide is also elaborated in the chapter.
64 citations
TL;DR: In this article, the bridged metallocenes Me2Si(Me4C5H)2 and C2H4(Me2Si (Me4c5H))2 were reported.
Abstract: Metal Complexes with Bridged Permethylated Cyclopentadienyl Ligands
The preparation of the permethylated silyl-bridged dicyclopentadienyl ligands Me2Si(Me4C5H)2 (1) and C2H4(Me2Si(Me4C5H))2 (2) is reported. Reaction of dimetalated 1 with TiCl4 and ZrCl4 yielded the corresponding metallocenophane dihalides 3 and 4, while treatment of the dilithio derivative of 2 with GeCl2 · dioxane, SnCl2, and FeCl2 yielded the bridged metallocenes 5, 6, and 7.
62 citations
58 citations
TL;DR: Evidence is presented that this compound is also present in the toad plasma and it is suggested that the endogenous bufodienolide derivative participates in the physiological regulation of the Na+,K+-ATPase activity.
57 citations
TL;DR: In this paper, an anti-Markovnikov addition reaction was used to transform α-vinyl-β-lactams involving an anti Markov addition reaction to terminal aldehydes instead of the expected methyl ketones.
52 citations
Patent•
31 Jan 1986TL;DR: In this paper, a heat-sensitive recording material is disclosed, comprising a support having thereon a heatsensitive, color-forming layer mainly composed of as colour-forming components a colorless or pale-colored leuco dye and an acidic compound capable of allowing said leluco dye to color develop by heating, wherein said heat sensitive, colorforming layer comprises a color former comprising a fluoran derivative represented by the following general formula (I) : wherein R1 and R2 each represent a lower alkyl group, and X represents a halogen atom, a
Abstract: of EP0211968A heat-sensitive recording material is disclosed, comprising a support having thereon a heat-sensitive, color-forming layer mainly composed of as color-forming components a colorless or pale-colored leuco dye and an acidic compound capable of allowing said leuco dye to color develop by heating, wherein said heat-sensitive, color-forming layer comprises a color former comprising a fluoran derivative represented by the following general formula (I) : wherein R1 and R2 each represents a lower alkyl group, and X represents a halogen atom, a lower alkyl group, a cyano group, or a nitro group, a developer comprising bis(p-hydroxyphenyl)sulfone or a derivative thereof represented by the following general formula (II) : wherein R3 and R4 each represents a hydrogen atom, an alkyl group, an aryl group, an alkoxy group, a phenoxy group, a carbonyl group, a nitro group, or a cyano group, and a binder comprising an ammonium salt of a diisobutylene/maleic anhydride copolymer and a styrene/ butadiene copolymer The heat-sensitive recording material of the present invention is good in preservability
51 citations
TL;DR: The structure of the tribenzyl derivative, determined by X-ray methods, shows some evidence of a CH2⋯ Ti interaction as mentioned in this paper, which is a strong indicator of the presence of CH2 interaction.
Abstract: Titanium pentamethylcyclopentadienyl trialkyls (η5-C5Me5)TiR3(R = Me, CH2SiMe3, C6F5, and CH2Ph) are easily obtained by conventional alkylation of the trichloro analogue; the structure of the tribenzyl derivative, determined by X-ray methods, shows some evidence of a CH2⋯ Ti interaction.
Patent•
06 May 1986
TL;DR: In this article, the authors proposed a method to obtain the titled polymer where the stereoregular structure of side chains have a syndiotactic configuration, by polymerizing styrene (derivative) in the presence of a catalyst component comprising a titanium compound and a specified product of contact.
Abstract: PURPOSE: To obtain the titled polymer where the stereoregular structure of side chains have a syndiotactic configuration, by polymerizing styrene (derivative) in the presence of a catalyst component comprising a titanium compound and a specified product of contact. CONSTITUTION: An organoaluminum compound (e.g., trimethylaluminum) is contacted with a condensing agent (e.g., water) to obtain a product of contact (ii). A titanium compound (i) selected from titanium (chelate) compounds of formulas I and II [wherein R 1W3 are each H, a 1W20C alkyl, a 1W20C alkoxy, a 6W20C aryl, an alkylaryl, arylalkyl, a 1W20C acyloxy, a (substituted) cyclopentadienyl or indenyl, X 1 is a halogen, a, b and c are each 0W4, and d and e are each 0W3] is contacted with component (ii) at a molar ratio of Al of component (ii) to Ti of component (i) of 1W10 6 to obtain a catalyst component. Styrene (derivative) is polymerized at 0W90°C in the presence of this component. COPYRIGHT: (C)1987,JPO&Japio
TL;DR: Observations suggest an iron‐catalyzed Haber‐Weiss reaction, involving superoxide and hydrogen peroxide in the generation of hydroxyl radicals, and apparently a porphyrin radical, formed via photoexcitation of hematoporphyr in derivative, could replace superoxide in this reaction.
Abstract: In a reaction mixture containing hematoporphyrin derivative, deoxyribose, Fe3+-EDTA and either methionine or tryptophan, hydroxyl radicals were formed during illumination with visible light. When either hematoporphyrin derivative, Fe3+-EDTA or the amino acid was omitted from the reaction mixture, the generation of hydroxyl radicals ceased. These observations suggest an iron-catalyzed Haber-Weiss reaction, involving superoxide and hydrogen peroxide in the generation of hydroxyl radicals. It could be shown that with methionine H2O2 was indeed an essential intermediate in the reaction sequence. With tryptophan, however, H2O2, was not generated. Apparently a photooxidation product of tryptophan could replace H2O2 in the OH-generating reaction with Fe2+-EDTA. Although superoxide was generated in the reaction mixture, it was not an indispensable intermediate. Apparently a porphyrin radical, formed via photoexcitation of hematoporphyrin derivative, could replace superoxide in the Haber-Weiss reaction.
Patent•
20 May 1986
TL;DR: In this article, a chewing gum containing freely dispersed L-aspartic acid sweetening agent derivative, moisture, and optionally, a manufacturing heat history of at least 115° F, is rendered storage stable relative to the retention of recoverable levels of the L aspartic acids derivative by adding hydrogenated starch hydrolysate to the mixture.
Abstract: Comestible compositions such as chewing gum containing freely dispersed L-aspartic acid sweetening agent derivative, moisture, and optionally, a manufacturing heat history of at least 115° F., are rendered storage stable relative to the retention of recoverable levels of the L-aspartic acid derivative by adding freely dispersed hydrogenated starch hydrolysate thereto, thereby allowing for the effective use of relatively low levels of such L-aspartic acid derivative therein.
TL;DR: A 10-step synthesis of the pheromone and analogues from an acyclic derivative of D-Xylose is described in this article, where the analogues are derived from the same root.
TL;DR: In this paper, the asymmetric Diels-Alder reaction of naphthoquinone derivative and diene in the presence of chiral boron reagent derived from B(OMe) 3 and ( R, R )(+)-tartaric acid diamide has been described as a model for the enantioselective preparation of important tetracycline natural products.
Enel1
TL;DR: In this paper, solid fuel samples were characterized by their proximate and ultimate analyses and then subjected to heat in a thermobalance, both under air and nitrogen, and trends in weight loss were recorded by thermogravimetry (TG) and derivative DTG, showing the existence of good correlations between the VM FC, C H and (C + H) O ratios and both rate of weight loss data and the temperatures deduced from the burning and volatile release profiles.
TL;DR: The crystal structure of the complex catena-bis (6-amino-3-methyl-5-nitrosouraciIato-~,~,N',~)cadmium(II) has been determined as mentioned in this paper.
Abstract: The crystal structure of the complex catena-bis(~-6-amino-3-methyl-5-nitrosouraciIato-~,~,N',~)cadmium(II) has been determined. It crystallizes in the tetragonal space group P41212-0: with cell dimensions a = b = 7.885 (0) A, c = 26.359 (2) A, V = 1638.8 ( I ) A', and Z = 4. The structure was solved from diffractometer data by Patterson and Fourier methods and refined by full-matrix least squares to R = 0.018 for 1956 data. The structure consists of a sequence of complex polymeric sheets, linked by hydrogen bonds. Each ligand is coordinated to two different cadmium atoms, and each cadmium atom is coordinated by four pyrimidine ligands. These ligands are equivalent with one cadmium atom binding through N5 and 0 4 atoms, while the other cadmium atom binds through the N1 and 0 2 sites. The cadmium atom is eight-coordinated and shows a C, symmetry that can be described as a dodecahedron with the mmmm arrangement of ligands. The A vertices are all occupied by oxygen atoms and the B vertices by nitrogen atoms.
Patent•
23 Dec 1986
TL;DR: A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide, mitecide and fungicide, methods of making such compounds, insecticidal and fungicidal compositions containing them and methods of controlling pests and fungus by applying them.
Abstract: OF THE DISCLOSURE A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide, mitecide and fungicide, methods of making such compounds, insecticidal and fungicidal compositions containing them and methods of controlling pests and fungus by applying them.
TL;DR: The most stable conformation of denticulatolide (1), an ichthyotoxic cembranolide, obtained as a major metabolite of the soft coral, Lobophytum denticula, was given by molecular mechanics calculations and it was confirmed by 1H NMR measurement.
TL;DR: A new antibiotic and antifungal derivative of 3,5-dibromo-tyrosine was isolated from the sponge Ianthella ardis, collected in Bahamas, and the structure has been established by spectral data as discussed by the authors.
TL;DR: In the presence of lithium hydride 6-(β-methoxyethoxy)guanine reacts regioselectively with 4-bromobutyl acetate to give the 9-alkyl guanine derivative as mentioned in this paper.
TL;DR: In this article, the authors calculate impurity effects from the initial slope of the critical line or from the dew-bubble curve for both nonaqueous and aqueous mixtures.
TL;DR: The title compound was synthesized by the diastereoselective addition of the lithium or sodium anion of dimethyl methylphosphonate to N -trityl-L-phenylalaninal as discussed by the authors.
Patent•
15 Dec 1986TL;DR: In this article, the authors describe a process for preparing a malonic acid derivative compound of formula (i) depicted herein in high yield and high purity by reacting it with an alkylating agent in the presence of a solvent and a base.
Abstract: This invention relates to a process for preparing a malonic acid derivative compound of formula (i) depicted herein in high yield and high purity by reacting a malonic acid derivative compound of formula (ii) depicted herein with an alkylating agent of formula (iii) depicted herein in the presence of a solvent and a base
TL;DR: The resin of Commiphora incisa (Burseraceae) has yielded three C22 compounds derived by loss of the C-17 side chain from a dammarane triterpene.