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Detection limit

About: Detection limit is a research topic. Over the lifetime, 34379 publications have been published within this topic receiving 644817 citations. The topic is also known as: limit of detection & lower detection limit.


Papers
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Journal ArticleDOI
TL;DR: The proposed FTO-AuNPs nanosensor can be used as a quantitative tool for rapid, on-site detection of chlorpyrifos traces in real samples when miniaturized due to its excellent stability, sensitivity, and simplicity.

113 citations

Journal ArticleDOI
01 Apr 2018-Talanta
TL;DR: The practicality and viability of this fluorescent probe were demonstrated through the analysis of silver ion in real river water and human serum samples and the prepared S,N-CQDs possessed low cytotoxicity and good biocompatibility.

113 citations

Journal ArticleDOI
TL;DR: In this paper, a sensor was developed that selectively catalyses the oxidation of l -ascorbic acid at low potentials (+100mV) to minimise the effects of many common electrochemical interferents.

113 citations

Journal ArticleDOI
TL;DR: In the case of serotonin, detection limits as low as 78 nM and 17 microM have been obtained for serotonin and histamine, respectively, which represents the lowest detection limit for a neurotransmitter by microchip electrophoresis with amperometric detection and the first report of amperomet detection of histamine detection at an unmodified platinum electrode.
Abstract: A method of electrochemically cleaning noble metal electrodes is presented and characterized for electrophoresis microchips with electrochemical detection. First, the loss of sensitivity due to electrode fouling by serotonin is characterized as a function of injection number and analyte concentration. Signal attenuation is observed to be greater at high concentrations (100 μM) and negligible at very low concentrations (∼1 μM). Next, an electrochemical treatment procedure is optimized to yield sensitive and reproducible amperometric detection of the highly adsorptive compounds, serotonin and histamine. Thus, the performance of the electrode is reproducibly regenerated following as much as a ∼99% reduction in surface activity. Utilizing the optimized three-level waveform, derived from that used for pulsed amperometric detection, detection limits as low as 78 nM and 17 μM have been obtained for serotonin and histamine, respectively. In the case of serotonin, this represents the lowest detection limit for a n...

113 citations

Journal ArticleDOI
TL;DR: In this paper, the use of indirect fluorescence detection for capillary zone electrophoresis was extended to the visible region, which is not based upon any absorption or emission properties of the analyte, therefore the need for chemical derivatization is eliminated.

113 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20241
20236,071
202212,796
20211,671
20201,442
20191,445