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Detection limit

About: Detection limit is a research topic. Over the lifetime, 34379 publications have been published within this topic receiving 644817 citations. The topic is also known as: limit of detection & lower detection limit.


Papers
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Journal ArticleDOI
TL;DR: The HPLC-ED method compared favorably with a negative chemical ionization GC-MS method previously utilized for analysis of olanzapine in human plasma and was applied to human plasma samples from human clinical trials with olanZapine.

100 citations

Journal ArticleDOI
TL;DR: In this article, the synthesis of boron and nitrogen Co-doped carbon nanoparticles (BN-CNPs) by a hydrothermal method using sucrose, boric acid, and urea as the precursors was reported.
Abstract: Here, we report the synthesis of boron and nitrogen Co-doped carbon nanoparticles (BN-CNPs) by a hydrothermal method using sucrose, boric acid, and urea as the precursors. The BN-CNPs show excellent photoluminescence with a quantum yield of ∼14.2% in aqueous solution and can be used as photoluminescent probes for selective and sensitive detection of picric acid (PA). PA quenches the photoluminescence signal remarkably, while other explosives cause a little quenching confirming the high selectivity of BN-CNPs. The sensitivity toward PA sensing is high at pH 7 and increases with temperature. The detection limit as well as the sensitivity are shown to improve by adding NaCl to the PA. The low detection limit can be as low as 10 nM at room temperature and pH 7, which indicates the BN-CNPs are superior as compared to other luminescent probes reported in the literature.

100 citations

Journal ArticleDOI
01 Jan 2001-Analyst
TL;DR: A modification of the aluminium-lumogallion fluorescence measurement in the presence of the non-ionic surfactant Triton X-100 is presented and is free from matrix effects and can be used for the determination of aluminium in fresh, estuarine and saline waters.
Abstract: A modification of the aluminium-lumogallion fluorescence measurement in the presence of the non-ionic surfactant Triton X-100 is presented. The detection limit for dissolved Al is 0.7 nM, with a relative standard deviation of 3.6% at an Al level of 5.0 nM. Compared with previously reported methods in the literature, the method described here is free from matrix effects and can be used for the determination of aluminium in fresh, estuarine and saline waters. The interferences from iron and fluoride were minimized by the addition of o-phenanthroline and Be2+, respectively. The analysis of NIST SRM 1643C and PRC standard 2430101 by the proposed method provides results consistent with the certified values. A successful inter-laboratory calibration exercise also demonstrates the merit of the proposed method for the determination of Al in environmental and marine sciences.

100 citations

Journal ArticleDOI
TL;DR: Capillary zone electrophoresis was employed for the determination of cysteine using an end-column amperometric detection with a gold/mercury amalgam microelectrode, at a constant potential of 0.02-0.06 V vs. saturated calomel electrode, and found to be linear over four orders of magnitude.

100 citations

Journal ArticleDOI
Yuliang Pan1, Manli Guo1, Zhou Nie1, Yan Huang1, Chunfeng Pan1, Kai Zeng1, Yu Zhang1, Shouzhuo Yao1 
TL;DR: The sgc8c aptamer-conjugated MBs specifically binding to CCRF-CEM cells were used for target cell extraction from complex matrixes, and the magnet-QCM system was successfully applied for quantitative cell detection, requiring no further labeling of cells.

100 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20241
20236,071
202212,796
20211,671
20201,442
20191,445