Topic
Detection limit
About: Detection limit is a research topic. Over the lifetime, 34379 publications have been published within this topic receiving 644817 citations. The topic is also known as: limit of detection & lower detection limit.
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TL;DR: In this article, a high-sensitive cholesterol amperometric biosensor based on the immobilization of cholesterol oxidase (ChOx) onto the ZnO nanoparticles has been fabricated which shows a very high and reproducible sensitivity of 23.7mM.
210 citations
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TL;DR: A simple and sensitive colorimetric detection method for Hg(2+) ions with a tunable detection range based on DNA oligonucleotides and unmodified gold nanoparticles (DNA/AuNPs) sensing system is reported.
210 citations
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TL;DR: CIAME is a simple and rapid method for extraction and preconcentration of metal ions from water samples and can be applied for the sample solutions containing high concentration of salt and water miscible organic solvents and is much safer in comparison with the organic solvent extraction.
209 citations
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TL;DR: The selectivity and robustness of the LC-MS/MS method was demonstrated by a 1-year comparison of its analytical results with those obtained from the validated GC and LC multi-residue methods applied to more than 3500 routine samples.
208 citations
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TL;DR: A multifunctional chip based on surface-enhanced Raman scattering (SERS) that effectively captures, discriminates, and inactivates pathogenic bacteria and enabled sensitive and specific discrimination of Escherichia coli and Staphylococcus aureus from human blood.
Abstract: Herein, we present a multifunctional chip based on surface-enhanced Raman scattering (SERS) that effectively captures, discriminates, and inactivates pathogenic bacteria. The developed SERS chip is made of a silicon wafer decorated with silver nanoparticles and modified with 4-mercaptophenylboronic acid (4-MPBA). It was prepared in a straightforward manner by chemical reduction assisted by hydrogen fluoride etching, followed by the conjugation of 4-MPBA through AgS bonds. The dominant merits of the fabricated SERS chip include excellent reproducibility with a relative standard deviation (RSD) value smaller than 11.0 %, adaptable bacterial-capture efficiency (ca. 60 %) at low concentrations (500–2000 CFU mL−1), a low detection limit (down to a concentration of 1.0×102 cells mL−1), and high antibacterial activity (an antibacterial rate of ca. 97 %). The SERS chip enabled sensitive and specific discrimination of Escherichia coli and Staphylococcus aureus from human blood.
207 citations